leukocyte elastase

Preferred Label : leukocyte elastase;

MeSH definition : An enzyme that catalyzes the hydrolysis of proteins, including elastin. It cleaves preferentially bonds at the carboxyl side of Ala and Val, with greater specificity for Ala. EC 3.4.21.37.;

MeSH synonym : elastase, neutrophil; granulocyte elastase; neutrophil elastase; polymorphonuclear leukocyte elastase; elastase, leukocyte; elastase, polymorphonuclear leukocyte; leukocyte elastase, polymorphonuclear; pmn elastase; elastase, pmn; elastase, granulocyte; lysosomal elastase; elastase, lysosomal;

MeSH Related Number : 9004-06-2 (CAS RN);

Registry Number MeSH : EC 3.4.21.37;

Is substance : O;

UNII : EC 3.4.21.37;

Details

Origin ID

D019272;

UMLS CUI

C0064833;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Elastase.leukocyte [LOINC component]
- Leukocyte elastase (substance) [SNOMED CT concept]
- leukocyte elastase [SNOMED Notion]
Indexing information
- ((4-methoxyphenyl)carbonyl)-valyl-N-(3-(1,1,1-trifluoro-2-hydroxy-4-methylpentyl))prolinamide [MeSH Supplementary Concept]
- 2-(3-methylsulfonylamino-2-oxo-6-phenyl-1,2-dihydro-1-pyridyl)-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide [MeSH Supplementary Concept]
- 2-(6'-methoxy-3',4'-dihydro-1'-naphthyl)-4H-3,1-benzoxazin-4-one [MeSH Supplementary Concept]
- 4-((((4-chloro-3-(((((4-hydroxy-3,5-di-tert-butylphenyl)thio)acetyl)amino)sulfonyl)phenyl)carbonyl)amino)sulfonyl)benzoyl-valyl-(perhydroindole-2-carbonyl)-valine trifluoromethyl ketone [MeSH Supplementary Concept]
- 4-chloro-7-(iodoacetyl)amino-3-methoxyisocoumarin [MeSH Supplementary Concept]
- 6-O-p-methoxycinnamoyl scandoside methyl ester [MeSH Supplementary Concept]
- FK 706 [MeSH Supplementary Concept]
- FR 901277 [MeSH Supplementary Concept]
- GW 311616 [MeSH Supplementary Concept]
- KRP-109 [MeSH Supplementary Concept]
- N-((5-(methanesulfonyl)pyridin-2-yl)methyl)-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamide [MeSH Supplementary Concept]
- NX 21909 [MeSH Supplementary Concept]
- ONO 6818 [MeSH Supplementary Concept]
- SYN 1390 [MeSH Supplementary Concept]
- SYN 1396 [MeSH Supplementary Concept]
- ZD 8321 [MeSH Supplementary Concept]
- cereoaldomine [MeSH Supplementary Concept]
- cereolactam [MeSH Supplementary Concept]
- depelestat [MeSH Supplementary Concept]
- flurithromycin [MeSH Supplementary Concept]
- iris protein, ixodes ricinus [MeSH Supplementary Concept]
- isodeoxyhelicobasidin [MeSH Supplementary Concept]
- pterolinus K [MeSH Supplementary Concept]
- pterolinus L [MeSH Supplementary Concept]
- trypethelone [MeSH Supplementary Concept]
Record concept(s)
- leukocyte elastase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ELANE protein, human [MeSH Supplementary Concept]
- Elane protein, mouse [MeSH Supplementary Concept]
- Elane protein, rat [MeSH Supplementary Concept]
- alpha 1-antitrypsin-leukocyte elastase complex [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Elastase.leukocyte [LOINC component]
- Leukocyte elastase (substance) [SNOMED CT concept]
- leukocyte elastase [SNOMED Notion]
Validated automatic mappings to BTNT
- Neutrophil Elastase [NCIt concept]

Keyword's position in hierarchy(ies) :

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