troponin c - CISMeF

Preferred Label : troponin c;

MeSH definition : One of the three polypeptide chains that make up the TROPONIN complex of skeletal muscle. It is a calcium-binding protein.; A TROPONIN complex subunit that binds calcium and help regulate calcium-dependent muscle contraction. There are two troponin C subtypes: troponin C1 and C2. Troponin C1 is skeletal and cardiac type whereas troponin C2 is skeletal type. Troponin C1 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin C1 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.;

MeSH synonym : Troponin-C;

DeCS synonym : Troponin C1; Troponin C2;

MeSH annotation : TROPONIN I & TROPONIN T are also available;

Is substance : O;

Details

Origin ID

D019209;

UMLS CUI

C0077400;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Troponin [FMA entity]
- Troponin [MedDRA Preferred Term]
- Troponin (substance) [SNOMED CT concept]
- Troponin C [MedDRA Preferred Term]
- Troponin C (substance) [SNOMED CT concept]
- Troponin I [MedDRA Preferred Term]
- Troponin T [MedDRA Preferred Term]
- Troponin-C [FMA entity]
- troponin c [SNOMED Notion]
- troponin i [SNOMED Notion]
- troponin t [SNOMED Notion]
- troponin, nos [SNOMED Notion]
Record concept(s)
- Troponin C1 [MeSH concept]
- Troponin C2 [MeSH concept]
- troponin C [MeSH concept]
Related MeSH Supplementary Concept(s)
- PAT-10 protein, C elegans [MeSH Supplementary Concept]
- cardiomyopathy, familial hypertrophic, 13 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Troponin C (substance) [SNOMED CT concept]
- Troponin-C [FMA entity]
- troponin c [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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