antibodies, blocking

Preferred Label : antibodies, blocking;

MeSH definition : Antibodies that inhibit the reaction between ANTIGEN and other antibodies or sensitized T-LYMPHOCYTES (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IGE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by CYTOTOXIC T-LYMPHOCYTES have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989);

MeSH synonym : blocking antibodies;

Wikipedia automatic translation : Antibody-dependent enhancement;

MeSH hyponym : enhancing antibodies; Antibodies, Enhancing;

MeSH annotation : antibodies inhibiting reaction between antigen and other antibodies or sensitized T-lymphocytes: not for any antibody reaction to an antigen ( ANTIBODIES or specific antibody); do not coordinate with ANTIBODY FORMATION for /biosyn;

Wikipedia link : https://en.wikipedia.org/wiki/Antibody-dependent enhancement;

Is substance : O;

Details

Origin ID

D019138;

UMLS CUI

C0282682;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Inhibiting antibodies [MedDRA Preferred Term]
- facilitating antibody [COVID-19 Thesaurus concept]
Currated CISMeF NLP mapping
- Blocking Antibody [NCIt concept]
- Blocking antibody (substance) [SNOMED CT concept]
- blocking antibody [SNOMED Notion]
Indexing information
- Basiliximab [MeSH Descriptor]
- blocking factor [MeSH Supplementary Concept]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- antibodies, blocking [MeSH concept]
- enhancing antibodies [MeSH concept]
Related MeSH Supplementary Concept(s)
- 4C9 antibody, rat [MeSH Supplementary Concept]
- bimagrumab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
UMLS correspondences (same concept)
- Blocking Antibody [NCIt concept]
- Blocking antibody (substance) [SNOMED CT concept]
- blocking antibody [SNOMED Notion]

Keyword's position in hierarchy(ies) :

Main resources

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