fas Receptor - CISMeF

Preferred Label : fas Receptor;

MeSH definition : A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.; A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.;

MeSH synonym : fas receptors; fas antigen; apo 1 antigen; cd95 antigen; fas antigens; receptor, fas; tnfrsf6 receptor; receptor, tnfrsf6; tumor necrosis factor receptor superfamily, member 6; apo-1 antigen; cd95 antigens; receptors, fas; Antigens, CD95; Fas Cell Surface Death Receptor;

Is substance : O;

Details

Origin ID

D019014;

UMLS CUI

C0245662;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Currated CISMeF NLP mapping
- CD95 [LOINC component]
- Lymphocyte antigen CD95 (substance) [SNOMED CT concept]
- Tumor Necrosis Factor Receptor Superfamily Member 6 [NCIt concept]
- lymphocyte antigen cd95 [SNOMED Notion]
Indexing information
- CH-11 anti-fas antibody, human [MeSH Supplementary Concept]
- PHLDA1 protein, human [MeSH Supplementary Concept]
- Phlda1 protein, mouse [MeSH Supplementary Concept]
- anti-Fas monoclonal antibody [MeSH Supplementary Concept]
- faim protein, mouse [MeSH Supplementary Concept]
Record concept(s)
- fas Receptor [MeSH concept]
Related MeSH Supplementary Concept(s)
- APG101 [MeSH Supplementary Concept]
- FAS protein, human [MeSH Supplementary Concept]
- Fas protein, rat [MeSH Supplementary Concept]
- fas protein, mouse [MeSH Supplementary Concept]
See also
- autoimmune lymphoproliferative syndrome [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- CD95 [LOINC component]
- Lymphocyte antigen CD95 (substance) [SNOMED CT concept]
- lymphocyte antigen cd95 [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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