MeSH definition : A tumor necrosis factor receptor subtype found in a variety of tissues and on activated
LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral
immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple
ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain
that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.; A tumor necrosis factor receptor subtype found in a variety of tissues and on activated
LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral
immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple
ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain
that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations
in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.;
A tumor necrosis factor receptor subtype found in a variety of tissues and on activated
LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral
immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple
ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain
that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. A tumor necrosis factor receptor subtype found in a variety of tissues and on activated
LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral
immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple
ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain
that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations
in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.