CD59 Antigens - CISMeF

Preferred Label : CD59 Antigens;

MeSH definition : Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234);

MeSH synonym : homologous restriction factor 20; hrf20; protectin; membrane attack complex inhibition factor; membrane inhibitor of reactive lysis; cd59 antigen; macif; Antigens, CD59;

MeSH annotation : note entry term PROTECTIN; do not confuse with protectins, which are n-3PUFA-derived anti-inflammatory mediators; the SCR term protectin D1 is also available;

Wikipedia link : https://en.wikipedia.org/wiki/Cd59 antigens;

Is substance : O;

Details

Origin ID

D018957;

UMLS CUI

C0054966;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- CD59 Gene [NCIt concept]
- CD59 Glycoprotein [NCIt concept]
- CD59 cells [LOINC component]
- CD59 molecule (CD59 blood group) [ORDO Gene]
- CD59 wt Allele [NCIt concept]
- Cd59 antigen [OMIM gene]
- Homologous restriction factor (substance) [SNOMED CT concept]
- Lymphocyte antigen CD59 (substance) [SNOMED CT concept]
- Protectin [NCIt concept]
- membrane attack complex inhibitory factor [SNOMED Notion]
Indexing information
- cationic protein, urate-calcium oxalate stone, human [MeSH Supplementary Concept]
Pharmacological action(s)
- complement inactivating agents [MeSH Descriptor]
Record concept(s)
- CD59 Antigens [MeSH concept]
Related MeSH Supplementary Concept(s)
- CD59 protein, human [MeSH Supplementary Concept]
- CD59a protein, mouse [MeSH Supplementary Concept]
- CD59b protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD59 [LOINC component]
- CD59.deficient [LOINC component]
- Lymphocyte antigen CD59 (substance) [SNOMED CT concept]
- lymphocyte antigen cd59 [SNOMED Notion]
- membrane attack complex inhibitory factor [SNOMED Notion]

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