hexamethonium - CISMeF

Preferred Label : hexamethonium;

MeSH definition : A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.;

MeSH synonym : hexonium;

CISMeF synonym : 60-25-3 (Hexamethonium chloride);

MeSH hyponym : hexamethonium bitartrate; depressin; hexamethonium dibromide; hexamethonium iodide; hexamethonium dihydroxide; hexamethonium monotartrate; hexamethonium chloride; hexamethonium diperchlorate; hexamethonium diiodide; hexamethonium bromide; hexamethonium dibromide dihydrate; hexamethonium dichloride dihydrate; hexamethonium dimethylsulfate; Dihydroxide, Hexamethonium; Diiodide, Hexamethonium; Dimethylsulfate, Hexamethonium; Diperchlorate, Hexamethonium; Iodide, Hexamethonium; Dibromide Dihydrate, Hexamethonium; Dihydrate, Hexamethonium Dibromide; Bitartrate, Hexamethonium; Bromide, Hexamethonium; Chloride, Hexamethonium; Dibromide, Hexamethonium; Dichloride Dihydrate, Hexamethonium; Dihydrate, Hexamethonium Dichloride; Monotartrate, Hexamethonium;

MeSH CAS label : 1,6-hexanediaminium, N,N,N,N',N',N'-hexamethyl-;

MeSH Related Number : hexamethonium dibromide; hexamethonium dichloride dihydrate; hexamethonium monotartrate; hexamethonium dihydroxide; hexamethonium diiodide; hexamethonium dimethylsulfate; hexamethonium diperchlorate; hexamethonium dibromide dihydrate; hexamethonium bitartrate; hexamethonium chloride; 16986-49-5 (dichloride dihydrate); 2079-78-9 (bitartrate); 5187-74-6 (dibromide dihydrate); 55-97-0 (dibromide); 556-81-0 (dihydroxide); 56503-18-5 (dimethylsulfate); 60-25-3 (chloride); 60-26-4 (Hexamethonium); 78995-78-5 (diperchlorate); 815-76-9 (monotartrate); 870-62-2 (diiodide); hexamethonium iodide; hexamethonium bromide; 8J77X3S603; G2753KSN40; TIV4Q933FU;

Registry Number MeSH : 60-26-4;

Related CAS MeSH : 556-81-0 (Hexamethonium dihydroxide); 870-62-2 (Hexamethonium diiodide); 56503-18-5 (Hexamethonium dimethylsulfate); 78995-78-5 (Hexamethonium diperchlorate); 5187-74-6 (Hexamethonium dibromide dihydrate); 2079-78-9 (Hexamethonium bitartrate); 55-97-0 (Hexamethonium dibromide); 16986-49-5 (Hexamethonium dichloride dihydrate); 815-76-9 (Hexamethonium monotartrate); G2753KSN40 (Hexamethonium iodide); 8J77X3S603 (Hexamethonium bromide); TIV4Q933FU (Hexamethonium chloride);

Wikipedia link : https://en.wikipedia.org/wiki/Hexamethonium;

Is substance : O;

UNII : 3C9PSP36Z2;

InChIKey : VZJFGSRCJCXDSG-UHFFFAOYSA-N;

Details

Origin ID

D018738;

UMLS CUI

C0062637;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Hexamethonium Bromide [NCIt concept]
- Hexamethonium Chloride [NCIt concept]
- Hexamethonium Iodide [NCIt concept]
- Hexamethonium bromide [ICHI extension code]
- hexamethonium bromide [Substance BNPC]
- hexamethonium chloride [Substance BNPC]
- hexamethonium iodide [Substance BNPC]
Currated CISMeF NLP mapping
- Hexamethonium [NCIt concept]
- Hexamethonium (substance) [SNOMED CT concept]
- hexamethonium [SNOMED Notion]
Pharmacological action(s)
- antihypertensive agents [MeSH Descriptor]
- ganglionic blockers [MeSH Descriptor]
- nicotinic antagonists [MeSH Descriptor]
- peripheral nervous system agents [MeSH Descriptor]
Record concept(s)
- depressin [MeSH concept]
- hexamethonium [MeSH concept]
- hexamethonium bitartrate [MeSH concept]
- hexamethonium bromide [MeSH concept]
- hexamethonium chloride [MeSH concept]
- hexamethonium dibromide [MeSH concept]
- hexamethonium dibromide dihydrate [MeSH concept]
- hexamethonium dichloride dihydrate [MeSH concept]
- hexamethonium dihydroxide [MeSH concept]
- hexamethonium diiodide [MeSH concept]
- hexamethonium dimethylsulfate [MeSH concept]
- hexamethonium diperchlorate [MeSH concept]
- hexamethonium iodide [MeSH concept]
- hexamethonium monotartrate [MeSH concept]
Related MeSH term(s)
- hexamethonium compounds [MeSH Descriptor]
See also (suggested by CISMeF)
- hexamethonium compounds [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Hexamethonium [NCIt concept]
- Hexamethonium (substance) [SNOMED CT concept]
- hexamethonium [SNOMED Notion]
Validated automatic mappings to BTNT
- Hexamethonium bromide [ICD-11 Extension code]

Keyword's position in hierarchy(ies) :

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