MeSH definition : Agents having as their major action the interruption of neural transmission at nicotinic
receptors on postganglionic autonomic neurons. Because their actions are so broad,
including blocking of sympathetic and parasympathetic systems, their therapeutic use
has been largely supplanted by more specific drugs. They may still be used in the
control of blood pressure in patients with acute dissecting aortic aneurysm and for
the induction of hypotension in surgery.;
Agents having as their major action the interruption of neural transmission at nicotinic
receptors on postganglionic autonomic neurons. Because their actions are so broad,
including blocking of sympathetic and parasympathetic systems, their therapeutic use
has been largely supplanted by more specific drugs. They may still be used in the
control of blood pressure in patients with acute dissecting aortic aneurysm and for
the induction of hypotension in surgery.