MeSH definition : A mass-spectrometric technique that is used for microscopic chemical analysis. A beam
of primary ions with an energy of 5-20 kiloelectronvolts (keV) bombards a small spot
on the surface of the sample under ultra-high vacuum conditions. Positive and negative
secondary ions sputtered from the surface are analyzed in a mass spectrometer in regards
to their mass-to-charge ratio. Digital imaging can be generated from the secondary
ion beams and their intensity can be measured. Ionic images can be correlated with
images from light or other microscopy providing useful tools in the study of molecular
and drug actions.;
MeSH synonym : secondary ion mass spectroscopy; secondary ion mass spectroscopy microscopy; sims microscopy; spectroscopy, mass, secondary ion; mass spectrometry, secondary ion; mass spectroscopy, secondary ion; secondary ion mass spectrometry; secondary ion mass spectrometry microscopy;
MeSH annotation : for SIMS microscopy, coordinate with type of microscopy;
Wikipedia link : https://en.wikipedia.org/wiki/Spectrometry, mass, secondary ion;
A mass-spectrometric technique that is used for microscopic chemical analysis. A beam
of primary ions with an energy of 5-20 kiloelectronvolts (keV) bombards a small spot
on the surface of the sample under ultra-high vacuum conditions. Positive and negative
secondary ions sputtered from the surface are analyzed in a mass spectrometer in regards
to their mass-to-charge ratio. Digital imaging can be generated from the secondary
ion beams and their intensity can be measured. Ionic images can be correlated with
images from light or other microscopy providing useful tools in the study of molecular
and drug actions.