alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

Preferred Label : alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid;

MeSH definition : An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.;

MeSH synonym : ampa; alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid;

Wikipedia automatic translation : Amputation;

MeSH hyponym : AMPA, ( -)-Isomer; AMPA, (S)-Isomer; AMPA, (R)-Isomer; AMPA, (R)-Isomer, monohydrobromide; AMPA, (S)-Isomer, monohydrobromide;

MeSH CAS label : 4-Isoxazolepropanoic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo-;

MeSH Related Number : AMPA, (R)-Isomer; AMPA, (S)-Isomer; AMPA, (S)-Isomer, monohydrobromide; AMPA, ( -)-Isomer; AMPA, (R)-Isomer, monohydrobromide; 74341-63-2 (( -)-isomer); 83643-88-3 ((S)-isomer); 83654-13-1 ((R)-isomer); 84799-50-8 ((R)-isomer, mono-HBr); 84799-52-0 ((S)-isomer, mono-HBr);

Registry Number MeSH : 77521-29-0;

Related CAS MeSH : 83654-13-1 (AMPA, (R)-Isomer); 83643-88-3 (AMPA, (S)-Isomer); 84799-52-0 (AMPA, (S)-Isomer, monohydrobromide); 74341-63-2 (AMPA, ( -)-Isomer); 84799-50-8 (AMPA, (R)-Isomer, monohydrobromide);

MeSH annotation : DF: note short X ref;

Wikipedia link : https://en.wikipedia.org/wiki/Amputation;

Is substance : O;

Details

Origin ID

D018350;

UMLS CUI

C0051318;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- 6,7-dichloro-2(1H)-oxoquinoline-3-phosphonic acid [MeSH Supplementary Concept]
Pharmacological action(s)
- excitatory amino acid agonists [MeSH Descriptor]
- neurotransmitter agents [MeSH Descriptor]
Record concept(s)
- AMPA, (+-)-Isomer [MeSH concept]
- AMPA, (R)-Isomer [MeSH concept]
- AMPA, (R)-Isomer, monohydrobromide [MeSH concept]
- AMPA, (S)-Isomer [MeSH concept]
- AMPA, (S)-Isomer, monohydrobromide [MeSH concept]
- alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2-amino-3-(3-hydroxy-4-isoxazoyl)propionic acid [MeSH Supplementary Concept]
- 2-amino-3-(3-hydroxy-5-(2-benzyl-2H-5-tetrazolyl)-4-isoxazolyl)propionic acid [MeSH Supplementary Concept]
- 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid [MeSH Supplementary Concept]
- alpha-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)methyl-5-methyl-3-oxo-4-isoxazoline-4-propionic acid [MeSH Supplementary Concept]
- alpha-amino-3-carboxymethoxy-5-methyl-4-isoxazolepropionic acid [MeSH Supplementary Concept]
- org 26576 [MeSH Supplementary Concept]
See also
- receptors, ampa [MeSH Descriptor]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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