B7-1 Antigen - CISMeF

Preferred Label : B7-1 Antigen;

MeSH definition : A costimulatory ligand expressed by ANTIGEN-PRESENTING CELLS that binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.; A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.;

MeSH synonym : b7-1 costimulatory molecule; b7 1 antigen; cd80 antigen; b-cell activation antigen; b cell activation antigen; cd80 antigens; b7 1 costimulatory molecule; costimulatory molecule, b7-1; antigen, b7-1; antigen, b7 1; B7-1 ligand; B7 1 ligand; ligand, B7-1; Antigens, CD80;

Is substance : O;

Details

Origin ID

D018122;

UMLS CUI

C0104998;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- CD80 Gene [NCIt concept]
- Cd80 antigen [OMIM gene]
Currated CISMeF NLP mapping
- CD80 [LOINC component]
- Lymphocyte antigen CD80 (substance) [SNOMED CT concept]
- lymphocyte antigen cd80 [SNOMED Notion]
Indexing information
- B-G antigen, gallus gallus [MeSH Supplementary Concept]
- CD80-CAP [MeSH Supplementary Concept]
Record concept(s)
- B7-1 Antigen [MeSH concept]
Related MeSH Supplementary Concept(s)
- CD80 protein, human [MeSH Supplementary Concept]
See also
- CD28 Antigens [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD80 [LOINC component]
- Lymphocyte antigen CD80 (substance) [SNOMED CT concept]
- lymphocyte antigen cd80 [SNOMED Notion]
Validated automatic mappings to BTNT
- T-Lymphocyte Activation Antigen CD80 [NCIt concept]

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