superantigens - CISMeF

Preferred Label : superantigens;

MeSH definition : Microbial antigens that have in common an extremely potent activating effect on T-cells that bear a specific variable region. Superantigens cross-link the variable region with class II MHC proteins regardless of the peptide binding in the T-cell receptor's pocket. The result is a transient expansion and subsequent death and anergy of the T-cells with the appropriate variable regions.;

MeSH synonym : Superantigen;

MeSH annotation : coordinate IM with specific microbe /immunol (IM); for interaction of superantigens with endotoxins, coordinate with ENDOTOXINS or specifics;

Wikipedia link : https://en.wikipedia.org/wiki/Superantigens;

Is substance : O;

Details

Origin ID

D018089;

UMLS CUI

C0206527;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Superantigen [NCIt concept]
Indexing information
- M12 protein, mouse mammary tumor virus [MeSH Supplementary Concept]
- MTV-48 protein, mouse mammary tumor virus [MeSH Supplementary Concept]
- MTV-51 protein, mouse mammary tumour virus [MeSH Supplementary Concept]
- Mtv-50 protein, mouse mammary tumor virus [MeSH Supplementary Concept]
- Mtv-7 superantigen, mouse mammary tumor virus [MeSH Supplementary Concept]
- Mtv29 protein, mouse [MeSH Supplementary Concept]
- Mtv8 protein, mouse [MeSH Supplementary Concept]
- SEGv enterotoxin [MeSH Supplementary Concept]
- SSL10 protein, Staphylococcus aureus [MeSH Supplementary Concept]
- Staphylococcal enterotoxin H [MeSH Supplementary Concept]
- enterotoxin A E-120, staphylococcal [MeSH Supplementary Concept]
- enterotoxin A, Staphylococcal [MeSH Supplementary Concept]
- enterotoxin B, staphylococcal [MeSH Supplementary Concept]
- enterotoxin C, staphylococcal [MeSH Supplementary Concept]
- enterotoxin E, Staphylococcal [MeSH Supplementary Concept]
- erythrogenic toxin [MeSH Supplementary Concept]
- mycoplasma arthritidis mitogen [MeSH Supplementary Concept]
- stinging nettle lectin [MeSH Supplementary Concept]
- streptococcus pyogenes mitogen-2 [MeSH Supplementary Concept]
- viral superantigen 23, mouse mammary tumor virus [MeSH Supplementary Concept]
- yersinia pseudotuberculosis-derived mitogen [MeSH Supplementary Concept]
- ypmB protein, yersinia pseudotuberculosis [MeSH Supplementary Concept]
Record concept(s)
- superantigens [MeSH concept]
Related MeSH Supplementary Concept(s)
- ERVK-18 protein, human [MeSH Supplementary Concept]
- GR protein, mouse mammary tumor virus [MeSH Supplementary Concept]
- PfiT protein, pseudomonas fluorescens [MeSH Supplementary Concept]
- SEIP protein, staphylococcus aureus [MeSH Supplementary Concept]
- SEQ protein, staphylococcus aureus [MeSH Supplementary Concept]
- SpeJ protein, streptococcus pyogenes [MeSH Supplementary Concept]
- SpeM protein, streptococcus pyogenes [MeSH Supplementary Concept]
- enterotoxin F, Staphylococcal [MeSH Supplementary Concept]
- enterotoxin G, staphylococcal [MeSH Supplementary Concept]
- enterotoxin I, staphylococcal [MeSH Supplementary Concept]
- mycoplasma arthritidis mitogen [MeSH Supplementary Concept]
- speL protein, streptococcus pyogenes [MeSH Supplementary Concept]
- toxic shock syndrome toxin 2, staphylococcus aureus [MeSH Supplementary Concept]
See also
- apoptosis [MeSH Descriptor]
- clonal anergy [MeSH Descriptor]
- receptors, antigen, t-cell, alpha-beta [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Superantigen [NCIt concept]

Keyword's position in hierarchy(ies) :

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