leukotriene c4

Preferred Label : leukotriene c4;

MeSH definition : The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990);

MeSH synonym : leukotriene c 4; leukotriene c-4; LTC4;

MeSH Hyperonym : leukotrienes C; Leukotriene C;

Related MeSH term : leukotriene C1; Leukotriene C-1; Leukotriene C 1;

MeSH CAS label : glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))-;

MeSH Related Number : 72025-60-6 (Leukotriene C4);

Registry Number MeSH : 72025-60-6;

MeSH annotation : /biosyn /physiol permitted; DF: note short X ref;

Is substance : O;

UNII : 2CU6TT9V48;

InChIKey : GWNVDXQDILPJIG-NXOLIXFESA-N;

Details

Origin ID

D017997;

UMLS CUI

C0023542;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Leukotriene C (substance) [SNOMED CT concept]
- leukotriene c [SNOMED Notion]
- leukotriene d [SNOMED Notion]
Record concept(s)
- leukotriene C1 [MeSH concept]
- leukotriene C4 [MeSH concept]
- leukotrienes C [MeSH concept]
Related MeSH Supplementary Concept(s)
- leukotriene C4 monomethyl ester [MeSH Supplementary Concept]
- leukotriene C4-iodo-4-azidosalicylic acid [MeSH Supplementary Concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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