MeSH definition : Cell surface receptors that bind somatomedins and trigger intracellular changes which
influence the behavior of cells. Studies have disclosed two types of receptors for
this family of peptide hormones. The type I receptor is homologous to the insulin
receptor and has tyrosine kinase activity. The type II receptor is identical to the
mannose-6-phosphate receptor which is important in trafficking of lysosomal enzymes.;
Cell surface receptors that bind somatomedins and trigger intracellular changes which
influence the behavior of cells. Studies have disclosed two types of receptors for
this family of peptide hormones. The type I receptor is homologous to the insulin
receptor and has tyrosine kinase activity. The type II receptor is identical to the
mannose-6-phosphate receptor which is important in trafficking of lysosomal enzymes.