Preferred Label : ribonucleoprotein, U1 small nuclear;
MeSH definition : A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm,
the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5)
assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA
forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes
both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two
sites for the splicing reaction.;
MeSH synonym : small nuclear ribonucleoproteins, u1; u1 small nuclear ribonucleoproteins; ribonucleoproteins, small, u1; u1 snrnp;
Is substance : O;
Origin ID : D017412;
UMLS CUI : C0162795;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Indexing information
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm,
the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5)
assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA
forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes
both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two
sites for the splicing reaction.
