Preferred Label : medroxyprogesterone acetate;

MeSH definition : A synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms.;

MeSH synonym : (6 alpha)-17-(acetoxy)-6-methylpregn-4-ene-3,20-dione; depo medroxyprogesterone acetate; 6-alpha-methyl-17alpha-hydroxyprogesterone acetate; 6 alpha methyl 17alpha hydroxyprogesterone acetate; Medroxyprogesterone 17-Acetate; medroxyprogesterone 17 acetate; depo-medroxyprogesterone acetate; Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6alpha)-;

CISMeF synonym : clinovir; 17-acetate, medroxyprogesterone; acetate, 6-alpha-methyl-17alpha-hydroxyprogesterone; acetate, depo-medroxyprogesterone; acetate, medroxyprogesterone;

MeSH hyponym : medroxyprogesterone 17-Acetate, (6 alpha,17 alpha)-Isomer; veramix; provera; farlutal; Depo-Provera; perlutex; curretab; cycrin; gestapuran; Depo Provera; DepoProvera;

Related MeSH term : medroxyprogesterone 17-Acetate, (6 beta)-Isomer;

MeSH CAS label : Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6alpha)-;

MeSH Related Number : medroxyprogesterone 17-Acetate, (6 alpha,17 alpha)-Isomer; medroxyprogesterone 17-Acetate, (6 beta)-Isomer; 1172-82-3 (cpd w/o isomeric designation); 2242-65-1 ((6 beta)-isomer); 560-12-3 ((6 alpha,17 alpha)-isomer); 71-58-9 (Medroxyprogesterone acetate);

Registry Number MeSH : 71-58-9;

Related CAS MeSH : 560-12-3 (Medroxyprogesterone 17-Acetate, (6 alpha,17 alpha)-Isomer); 2242-65-1 (Medroxyprogesterone 17-Acetate, (6 beta)-Isomer);

Wikipedia link : https://en.wikipedia.org/wiki/Medroxyprogesterone acetate;

Codes EINECS : 200-757-9;

Is substance : O;

UNII : C2QI4IOI2G;

InChIKey : PSGAAPLEWMOORI-PEINSRQWSA-N;

Details


Main resources

You can consult :

A synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms.

https://ansm.sante.fr/actualites/progestatifs-et-risque-de-meningiomes-intracraniens-le-bmj-publie-une-etude-epidemiologique-francaise
2024
false
false
false
France
French
pharmacovigilance note
epidemiologic studies
france
meningioma
meningioma
medroxyprogesterone acetate
risk assessment
Product containing only levonorgestrel in intrauterine dose form (medicinal product form)
levonorgestrel
injections, intramuscular
plastic iud with progestogen
administration, intravaginal
progestins
intrauterine devices
medroxyprogesterone

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https://ansm.sante.fr/actualites/progestatifs-et-risque-de-meningiome-recommandations-pour-limiter-ce-risque
2023
false
false
false
France
French
guideline
guidelines for drug use
medrogestone
medrogestone
meningioma
Drug-Related side effects and adverse reactions
medroxyprogesterone acetate
medroxyprogesterone acetate
progestins
progestins
continuity of patient care
patient safety
promegestone
risk management
risk factors

---
http://www.jogc.com/article/S1701-2163%2816%2900123-7/fulltext
http://www.jogc.com/article/S1701-2163%2816%2900123-7/pdf
2016
false
true
false
Canada
French
practice guideline
contraceptive agents, female
drug implants
drug implants
drug implants
contraceptive agents, female
contraceptive agents, female
medroxyprogesterone acetate
drug interactions
Contraindications, Drug

---
http://www.cochrane.org/fr/CD009849
http://www.cochrane.org/fr/CD009849/contraception-hormonale-et-risque-de-fracture-dans-les-etudes-observationnelles
2015
false
United Kingdom
France
French
risk assessment
meta-analysis
women
fractures, bone
french abstract
contraceptives, oral, hormonal
intrauterine devices, medicated
medroxyprogesterone acetate

---
http://www.has-sante.fr/portail/jcms/c_2038833/fr/depo-provera
http://www.has-sante.fr/portail/jcms/c_732208/depo-provera
2015
false
France
French
Delayed-Action preparations
medroxyprogesterone acetate
progesterone congeners
injections, intramuscular
contraceptive agents, female
medroxyprogesterone
insurance, health, reimbursement
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/jcms/c_1753126/fr/divina-duova
2014
false
France
French
postmenopause
estrogens
divina
drug combinations
administration, oral
medroxyprogesterone and estrogen
medroxyprogesterone and estrogen
medroxyprogesterone acetate
estradiol
hormone replacement therapy
insurance, health, reimbursement
estrogens
progesterone congeners
osteoporosis, postmenopausal
osteoporotic fractures
evaluation of the transparency committee
drug combinations
estradiol
medroxyprogesterone

---
http://www.lecrat.eu/?s=M%C3%A9droxyprogest%C3%A9rone+-+D%C3%A9po-prodasone%C2%AE%2C+D%C3%A9po-prov%C3%A9ra%C2%AE%2C+Farlutal%C2%AE
2013
France
French
medroxyprogesterone
pregnancy
contraceptives, oral, synthetic
injections, intramuscular
breast feeding
medroxyprogesterone acetate
drug combinations
divina
medroxyprogesterone
progesterone congeners
drug information

---
http://www.has-sante.fr/portail/jcms/c_1650020/fr/depo-prodasone
http://www.has-sante.fr/portail/jcms/c_1650019/fr/depo-prodasone-18092013-avis-ct8964
2013
France
French
evaluation of the transparency committee
insurance, health, reimbursement
medroxyprogesterone acetate
antineoplastic agents, hormonal
neoplasms, hormone-dependent
medroxyprogesterone
injections, intramuscular
endometrial neoplasms
breast neoplasms
neoplasm metastasis
adenocarcinoma
postmenopause
endometriosis

---
http://www.cochrane.org/fr/CD005214
2012
France
United Kingdom
French
french abstract
meta-analysis
medroxyprogesterone acetate
contraceptive agents, female
contraceptives, oral, synthetic
norethindrone
norethindrone enanthate
comparative study

---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-03/farlutal_-_ct-_8710.pdf
http://www.has-sante.fr/portail/jcms/c_1036297/farlutal
2011
France
French
medroxyprogesterone acetate
insurance, health, reimbursement
administration, oral
injections, intramuscular
medroxyprogesterone
antineoplastic agents, hormonal
neoplasms, hormone-dependent
endometrial neoplasms
breast neoplasms
treatment outcome
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/jcms/c_817325/divina-duova
http://www.has-sante.fr/portail/upload/docs/application/pdf/2009-07/divina_-_duova_-_ct-6669.pdf
2009
France
French
divina
drug combinations
administration, oral
medroxyprogesterone and estrogen
medroxyprogesterone and estrogen
medroxyprogesterone acetate
estradiol
hormone replacement therapy
insurance, health, reimbursement
estrogens
progesterone congeners
osteoporosis, postmenopausal
fractures, bone
evaluation of the transparency committee
estradiol

---
https://www.inspq.qc.ca/sites/default/files/publications/785-acetatemedroxyimpact.pdf
2008
Canada
French
scientific and technical information
medroxyprogesterone acetate
osteoporosis
contraceptive agents
fractures, bone
bone density
medroxyprogesterone acetate
contraceptive agents
consensus
risk assessment

---
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct-4575_diviseq.pdf
http://www.has-sante.fr/portail/display.jsp?id=c_574437
2007
France
French
tablets
drug combinations
medroxyprogesterone acetate
administration, oral
insurance, health, reimbursement
estrogens
medroxyprogesterone and estrogen
estrogen replacement therapy
treatment outcome
estradiol
evaluation of the transparency committee
estradiol

---
http://www.has-sante.fr/portail/display.jsp?id=c_545492
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct-4423_duova_.pdf
2007
France
French
administration, oral
drug combinations
insurance, health, reimbursement
medroxyprogesterone acetate
estrogens
medroxyprogesterone and estrogen
estradiol
treatment outcome
osteoporosis, postmenopausal
tablets
progesterone congeners
hormone replacement therapy
evaluation of the transparency committee
estradiol

---
https://www.jogc.com/article/S1701-2163(16)32126-0/abstract
2006
false
Canada
French
medroxyprogesterone acetate
contraceptive agents, female
canada
medroxyprogesterone acetate
bone density
adult
adolescent
fractures, bone
risk factors
practice guideline

---
http://www.has-sante.fr/portail/display.jsp?id=c_399382
2002
France
evaluation of the transparency committee
tablets
medroxyprogesterone acetate

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