MeSH definition : A family of synaptic vesicle-associated proteins involved in the short-term regulation
of NEUROTRANSMITTER release. Synapsin I, the predominant member of this family, links
SYNAPTIC VESICLES to ACTIN FILAMENTS in the presynaptic nerve terminal. These interactions
are modulated by the reversible PHOSPHORYLATION of synapsin I through various signal
transduction pathways. The protein is also a substrate for cAMP- and CALCIUM-CALMODULIN-DEPENDENT
PROTEIN KINASES. It is believed that these functional properties are also shared by
synapsin II.;
A family of synaptic vesicle-associated proteins involved in the short-term regulation
of NEUROTRANSMITTER release. Synapsin I, the predominant member of this family, links
SYNAPTIC VESICLES to ACTIN FILAMENTS in the presynaptic nerve terminal. These interactions
are modulated by the reversible PHOSPHORYLATION of synapsin I through various signal
transduction pathways. The protein is also a substrate for cAMP- and CALCIUM-CALMODULIN-DEPENDENT
PROTEIN KINASES. It is believed that these functional properties are also shared by
synapsin II.
Allowable qualifiers