talin - CISMeF

Preferred Label : talin;

MeSH definition : A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS; VINCULIN; and ACTINS and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton.;

MeSH synonym : band 2 protein; protein, band 2;

Wikipedia automatic translation : Talin, Armenia;

MeSH hyponym : platelet protein p235; Protein p235, Platelet;

MeSH annotation : a cytoplasmic protein; /drug eff /ultrastruct permitted;

Wikipedia link : https://en.wikipedia.org/wiki/Talin, Armenia;

Is substance : O;

Details

Origin ID

D016608;

UMLS CUI

C0085182;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Talin 1 [OMIM gene]
- ZNF365 wt Allele [NCIt concept]
Record concept(s)
- platelet protein p235 [MeSH concept]
- talin [MeSH concept]
Related MeSH Supplementary Concept(s)
- TLN1 protein, human [MeSH Supplementary Concept]
- TLN2 protein, human [MeSH Supplementary Concept]
- TLN2 protein, mouse [MeSH Supplementary Concept]
- Tln1 protein, mouse [MeSH Supplementary Concept]
- tln1 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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