HIV protease - CISMeF

Preferred Label : HIV protease;

MeSH definition : Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag and gag-pol precursor polyproteins into functional products needed for viral assembly. HIV protease is an aspartic protease encoded by the amino terminus of the pol gene.;

MeSH synonym : hiv proteinase; protease, htlv-iii; p16 protease, hiv; protease, hiv; p16 pol gene product, hiv; hiv p16 protease; htlv-iii protease; htlv iii protease;

Registry Number MeSH : EC 3.4.23.-;

Is substance : O;

Details

Origin ID

D016333;

UMLS CUI

C0079522;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Presenilin-1 [NCIt concept]
- Presenilin-2 [NCIt concept]
Indexing information
- (1-(N'-(4-hydroxy-4-(2-hydroxyindan-1-ylcarbamoyl)-5-phenylpentyl)-N'-(4-pyridin-4-ylbenzyl)hydrazinocarbonyl)-2,2-dimethylpropyl)carbamic acid methyl ester [MeSH Supplementary Concept]
- 3-(3-acetylphenyl)-N-(1-benzyl-2-hydroxy-3-(isobutyl((4-methoxyphenyl)sulfonyl)amino)propyl)-2-oxooxazolidine-5-carboxamide [MeSH Supplementary Concept]
- A 790742 [MeSH Supplementary Concept]
- N(alpha)-benzoyl-arginyl-glycyl-phenylalanyl-prolyl-methoxy-beta-naphthylamide [MeSH Supplementary Concept]
- N-(2''-hydroxy-2''-(4-hydroxy-16-oxo-7,8,9,10,11,12,13,14,15,16-decahydro-6H-5-oxa-15-azabenzocyclotetradecen-14-yl)ethyl)-N-isobutyl-4-methoxybenzenesulfonamide [MeSH Supplementary Concept]
- RO1 compound [MeSH Supplementary Concept]
- hexahydro-2H-furo(2,3-b)pyran-4-yl-(2S,3R)-4-(N-isobutyl-4-methoxyphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl carbamate [MeSH Supplementary Concept]
- hinnuliquinone [MeSH Supplementary Concept]
- methyl 1-(5-(2-(3-benzyl-2-oxoimidazolidin-1-yl)-3,3-dimethylbutanamido)-4-hydroxy-6-phenyl-1-(4-(pyridin-2-yl)phenyl)hexan-2-ylamino)-3,3-dimethyl-1-oxobutan-2-ylcarbamate [MeSH Supplementary Concept]
- tetrahydrofuranylcarbamatemonopyrrolinone [MeSH Supplementary Concept]
Record concept(s)
- HIV protease [MeSH concept]
Related MeSH Supplementary Concept(s)
- HIV-1 protease (44-48) [MeSH Supplementary Concept]
- HIV-1 protease (89-99) [MeSH Supplementary Concept]
- p16 protease, human immunodeficiency virus 1 [MeSH Supplementary Concept]
- p16 protease, human immunodeficiency virus 2 [MeSH Supplementary Concept]
Related MeSH term(s)
- hiv protease inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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