Proto-Oncogene proteins p21(ras)

Preferred Label : Proto-Oncogene proteins p21(ras);

MeSH definition : Cellular proteins encoded by the H-ras, K-ras and N-ras genes. The proteins have GTPase activity and are involved in signal transduction as monomeric GTP-binding proteins. Elevated levels of p21 c-ras have been associated with neoplasia. This enzyme was formerly listed as EC 3.6.1.47.;

MeSH synonym : proto-oncogene proteins c-ras; p21 c-ras; p21(ras); ras proto oncogene product p21; ras proto oncogene protein p21; c-ras, proto-oncogene proteins; proteins c-ras, proto-oncogene; c-ras proteins; c ras proteins; proto-oncogene protein p21(ras); c-ras, p21; p21 c ras; p21(c-ras); proto-oncogene protein ras; proto oncogene protein ras; ras, proto-oncogene protein; proto oncogene proteins c ras; ras proto-oncogene product p21; ras proto-oncogene protein p21;

MeSH hyponym : Proto-Oncogene protein p21(c-Ha-ras); Proto-Oncogene protein p21(c-Ki-ras); Proto-Oncogene protein p21(c-N-ras); p21(N-ras); p21 c-Ha-ras; c-Ha-ras, p21; p21 c Ha ras; p21(c-Ha-ras); p21 c-H-ras; c-H-ras, p21; p21 c H ras; c-Ha-ras p21; c Ha ras p21; p21, c-Ha-ras; p21 c-Ki-ras; c-Ki-ras, p21; p21 c Ki ras; p21(c-Ki-ras); p21 c-K-ras; c-K-ras, p21; p21 c K ras; c-Ki-ras p21; c Ki ras p21; p21, c-Ki-ras;

CISMeF hyponym : EC 2.6.1.-; EC 3.6.1.-;

MeSH Related Number : Proto-Oncogene protein p21(c-N-ras); Proto-Oncogene protein p21(c-Ha-ras); Proto-Oncogene protein p21(c-Ki-ras);

Registry Number MeSH : EC 3.6.5.2;

Related CAS MeSH : EC 3.6.1.- (Proto-Oncogene protein p21(c-N-ras)); EC 2.6.1.- (Proto-Oncogene protein p21(c-Ha-ras)); EC 3.6.1.- (Proto-Oncogene protein p21(c-Ki-ras));

Is substance : O;

UNII : EC 3.6.5.2;

Details

Origin ID

D016283;

UMLS CUI

C0080058;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Proto-Oncogene protein p21(c-Ha-ras) [MeSH concept]
- Proto-Oncogene protein p21(c-Ki-ras) [MeSH concept]
- Proto-Oncogene protein p21(c-N-ras) [MeSH concept]
- Proto-Oncogene proteins p21(ras) [MeSH concept]
Related MeSH Supplementary Concept(s)
- HRAS protein, human [MeSH Supplementary Concept]
- Hras protein, mouse [MeSH Supplementary Concept]
- KRAS protein, human [MeSH Supplementary Concept]
- KRAS4B protein, mouse [MeSH Supplementary Concept]
- Kras protein, zebrafish [MeSH Supplementary Concept]
- kras protein, rat [MeSH Supplementary Concept]
See also
- costello syndrome [MeSH Descriptor]
- genes, ras [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- p21 RAS Protein [NCIt concept]

Keyword's position in hierarchy(ies) :

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