endothelins - CISMeF

Preferred Label : endothelins;

MeSH definition : 21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.;

MeSH synonym : endothelin; vasoconstrictor factors, endothelium-derived; endothelium-derived vasoconstrictor factors;

MeSH annotation : GEN or unspecified; prefer specifics; /drug eff permitted; general or unspecified; prefer specifics;

Wikipedia link : https://en.wikipedia.org/wiki/Endothelin;

Is substance : O;

Details

Origin ID

D016232;

UMLS CUI

C0079284;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Endothelin [LOINC component]
- Endothelin [MedDRA Preferred Term]
- Endothelin Pathway [NCIt concept]
Indexing information
- 9-fluorenylmethoxycarbonyl-leucyl-aspartyl-isoleucyl-isoleucyl-tryptophan-OH [MeSH Supplementary Concept]
- TBC 3214 [MeSH Supplementary Concept]
- cyclo(leucyl-valyl-prolyl-aspartyl-tryptophan) [MeSH Supplementary Concept]
- cyclo(tryptophyl-aspartyl-acetyl(3)c-valyl-leucyl) [MeSH Supplementary Concept]
- cyclo(tryptophyl-aspartyl-prolyl-thianylglycyl-leucyl) [MeSH Supplementary Concept]
- endothelin-3 (1-41)amide [MeSH Supplementary Concept]
- methylendioxyphenyl [MeSH Supplementary Concept]
Record concept(s)
- endothelins [MeSH concept]
Related MeSH Supplementary Concept(s)
- BQ 3020 [MeSH Supplementary Concept]
- Cys(11)-Cys(15)-endothelin-1 (11-21) [MeSH Supplementary Concept]
- IRL 1720 [MeSH Supplementary Concept]
- N(epsilon)-9-azidobenzoyliodoendothelin-1 [MeSH Supplementary Concept]
- big endothelin-1 (19-37), Phe(22)- [MeSH Supplementary Concept]
- big endothelin-1(16-38), valine(22)- [MeSH Supplementary Concept]
- big-endothelin (1-22) [MeSH Supplementary Concept]
- big-endothelin (16-32) [MeSH Supplementary Concept]
- endothelin (16-21) [MeSH Supplementary Concept]
- endothelin (16-21) amide [MeSH Supplementary Concept]
- endothelin 1, Ala(1,15)- [MeSH Supplementary Concept]
- endothelin 1, Ala(1,3,11,15)- [MeSH Supplementary Concept]
- endothelin 1, Ala(3,11)- [MeSH Supplementary Concept]
- endothelin 1, Dpr(1)-Asp(15)- [MeSH Supplementary Concept]
- endothelin, Nle(7)- [MeSH Supplementary Concept]
- endothelin-1, Ala(9)- [MeSH Supplementary Concept]
- endothelin-1, Pro(12)- [MeSH Supplementary Concept]
- endothelin-1, Thr(18)-gamma-methyl-Leu(19)- [MeSH Supplementary Concept]
- endothelin-1,2-6-keto-PGF1-alpha [MeSH Supplementary Concept]
- endothelin7-21(Leu7,Aib11,Cys(Acm)15) [MeSH Supplementary Concept]
- preproendothelin 2 [MeSH Supplementary Concept]
- preproendothelin-3 [MeSH Supplementary Concept]
- proendothelin 2 [MeSH Supplementary Concept]
- proendothelin 3 [MeSH Supplementary Concept]
- proendothelin-1 (22-39) [MeSH Supplementary Concept]
- proendothelin-1 (31-38) [MeSH Supplementary Concept]
- sovateltide [MeSH Supplementary Concept]
See also
- receptors, endothelin [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Endothelin [LOINC component]

Keyword's position in hierarchy(ies) :

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