fibroblast growth factor 2

Preferred Label : fibroblast growth factor 2;

MeSH definition : A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).;

MeSH synonym : cartilage derived growth factor; cartilage-derived growth factor; class ii heparin-binding growth factor; fgf 2; fgf-2; fgf2; fibroblast growth factor, basic; hbgf-2; heparin-binding growth factor class ii; prostate epithelial cell growth factor; prostatropin; basic fibroblast growth factor; fibroblast growth Factor-2;

Registry Number MeSH : 103107-01-3;

MeSH annotation : DF: FGFB;

Is substance : O;

Details

Origin ID

D016222;

UMLS CUI

C0380603;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- 2,5-dihydroxyphenylsulfonate [MeSH Supplementary Concept]
- bis(8(4-(4-amino-1-methyl-1H-pyrrole-2-carbonylamino)-1-methyl-1H-pyrrole-2-carbonylamino)naphthalene-1,5-disulfonic acid) tetrasodium salt [MeSH Supplementary Concept]
Record concept(s)
- fibroblast growth factor 2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- FGF-P peptide [MeSH Supplementary Concept]
- KCB-1 protein, recombinant [MeSH Supplementary Concept]
- basic fibroblast growth factor-saporin mitotoxin, recombinant [MeSH Supplementary Concept]
- hexafin2 peptide [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Fibroblast growth factor 2 [LOINC component]

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