methacholine chloride

Preferred Label : methacholine chloride;

MeSH definition : A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116);

MeSH synonym : acetyl beta methacholine chloride; acetyl 2 methylcholine chloride; chloride, methacholine; acetyl-2-methylcholine chloride; mecholine; 2-(acetyloxy)-n,n,n-trimethyl-1-propanaminium chloride; acetyl-beta-methacholine chloride;

CISMeF synonym : 55-92-5 (Methacholine); roche brand of methacholine chloride; methapharma brand of methacholine chloride; lindopharm brand of methacholine chloride;

MeSH Hyperonym : methacholine; mecholyl; acetyl-beta-methylcholine; Acetyl beta methylcholine;

MeSH hyponym : provokit; provocholine;

MeSH CAS label : 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride;

MeSH Related Number : methacholine; 55-92-5 (parent); 62-51-1 (Methacholine chloride); 03V657ZD3V;

Registry Number MeSH : 62-51-1;

Related CAS MeSH : 03V657ZD3V (Methacholine);

Wikipedia link : https://en.wikipedia.org/wiki/Provocholine;

Codes EINECS : 200-537-2;

Is substance : O;

UNII : 0W5ETF9M2K;

InChIKey : JHPHVAVFUYTVCL-UHFFFAOYSA-M;

Details

Origin ID

D016210;

UMLS CUI

C0079829;

ATC code(s)
- methacholine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Methacholine [ICHI extension code]
- Methacholine [NCIt concept]
- Methacholine (substance) [SNOMED CT concept]
- methacholine [ATC Code]
- methacholine [SNOMED Notion]
CISMeF manual mappings
- methacholine chloride [Substance BNPC]
Pharmacological action(s)
- bronchoconstrictor agents [MeSH Descriptor]
- miotics [MeSH Descriptor]
- muscarinic agonists [MeSH Descriptor]
- parasympathomimetics [MeSH Descriptor]
- peripheral nervous system agents [MeSH Descriptor]
Record concept(s)
- acetyl-beta-methylcholine [MeSH concept]
- mecholyl [MeSH concept]
- methacholine [MeSH concept]
- methacholine chloride [MeSH concept]
- provocholine [MeSH concept]
- provokit [MeSH concept]
Related MeSH Supplementary Concept(s)
- esmodil [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- methacholine compounds [MeSH Descriptor]
See also inter- (CISMeF)
- Product containing methacholine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Methacholine Chloride [NCIt concept]
- Methacholine chloride (substance) [SNOMED CT concept]
- methacholine chloride [Substance BNPC]
Validated automatic mappings to NTBT
- Methacholine [ICD-11 Extension code]
- Methacholine [SMS substance]
- Methacholine [LOINC component]

Keyword's position in hierarchy(ies) :

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