CDC2 protein kinase

Preferred Label : CDC2 protein kinase;

MeSH definition : Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL CYCLE. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of cyclin-dependent kinase 1 is achieved when it is fully dephosphorylated.;

MeSH synonym : cdc2 protein; cdk1 protein kinase; protein kinase, cdc2; cyclin-dependent kinase 1; cyclin dependent kinase 1; protein kinase, cdk1; cdk1 kinase;

CISMeF synonym : EC 2.7.1.37;

MeSH hyponym : p34cdc2 protein; Protein p34cdc2; p34cdc2, Protein; Histone Kinase p34(cdc2);

MeSH Related Number : p34cdc2 protein; EC 2.7.11.22;

Registry Number MeSH : EC 2.7.11.22;

Related CAS MeSH : EC 2.7.11.22 (p34cdc2 protein);

Wikipedia link : https://en.wikipedia.org/wiki/Cyclin-dependent kinase 1;

Is substance : O;

UNII : EC 2.7.11.22;

Details

Origin ID

D016203;

UMLS CUI

C0080054;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- 2-((2-chlorophenyl)thio)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-4-piperidinyl)-4H-1-benzopyran-4-one [MeSH Supplementary Concept]
- 2-(2-chlorophenoxy)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-4-piperidinyl)-4H-1-benzopyran-4-one [MeSH Supplementary Concept]
- 3-(4-(4-(3-chlorophenylamino)-(1,3,5)triazin-2-yl)pyridin-2-ylamino)propan-1-ol [MeSH Supplementary Concept]
- 3-(7-(benzylamino)-3-isopropylpyrazolo(1,5-a)pyrimidin-5-ylamino)-1,2,4-butanetriol [MeSH Supplementary Concept]
- 4-amino-1-tert-butyl-3-(1'-naphthylmethyl)pyrazolo(3,4-d)pyrimidine [MeSH Supplementary Concept]
- 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine [MeSH Supplementary Concept]
- 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine [MeSH Supplementary Concept]
- BMI 1026 [MeSH Supplementary Concept]
- CDKL1 protein, human [MeSH Supplementary Concept]
- N-((5-(3-(4,6-difluoro-1H-benzimidazol-2-yl)-1H-indazol-5-yl)-4-methylpyridin-3-yl)methyl)ethanamine [MeSH Supplementary Concept]
- RO 3306 [MeSH Supplementary Concept]
- alsterpaullone [MeSH Supplementary Concept]
- bohemine [MeSH Supplementary Concept]
Record concept(s)
- CDC2 protein kinase [MeSH concept]
- p34cdc2 protein [MeSH concept]
Related MeSH Supplementary Concept(s)
- CDC2 peptide (9-19) [MeSH Supplementary Concept]
- CDC2A protein, arabidopsis [MeSH Supplementary Concept]
- CDK1 protein, human [MeSH Supplementary Concept]
- CDK13 protein, human [MeSH Supplementary Concept]
- CDK13 protein, mouse [MeSH Supplementary Concept]
- Cdk1 protein, Drosophila [MeSH Supplementary Concept]
- Cdk1 protein, mouse [MeSH Supplementary Concept]
- Cdk1 protein, rat [MeSH Supplementary Concept]
- Cys-cdc2 (8-20) [MeSH Supplementary Concept]
- PSTAIR peptide [MeSH Supplementary Concept]
- Pfcrk-1 protein, plasmodium falciparum [MeSH Supplementary Concept]
- cdc2 protein, S pombe [MeSH Supplementary Concept]
- cdc2(6-20)NH2 [MeSH Supplementary Concept]
- crk1 protein,Trypanosoma brucei [MeSH Supplementary Concept]
- crk2 protein, trypanosoma brucei [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cyclin-Dependent Kinase 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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