didanosine - CISMeF

Preferred Label : didanosine;

MeSH definition : A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.;

MeSH synonym : dideoxyinosine; 2',3' dideoxyinosine; 2',3'-dideoxyinosine; ddi (antiviral);

CISMeF synonym : Bristol-Myers squibb brand of didanosine; bristol myers squibb brand of didanosine; Bristol-Myers brand of didanosine; bristol myers brand of didanosine;

MeSH hyponym : videx; NSC-612049; NSC 612049; NSC612049;

MeSH CAS label : inosine, 2',3'-dideoxy-;

MeSH Related Number : 69655-05-6 (Didanosine);

Registry Number MeSH : 69655-05-6;

Wikipedia link : https://en.wikipedia.org/wiki/Didanosine;

Is substance : O;

UNII : K3GDH6OH08;

InChIKey : BXZVVICBKDXVGW-NKWVEPMBSA-N;

Details

Origin ID

D016049;

UMLS CUI

C0012133;

ATC code(s)
- didanosine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Didanosine adverse reaction (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Didanosine [LOINC component]
- Didanosine [ICD-11 Extension code]
- Didanosine [SMS substance]
- Didanosine [NCIt concept]
- Didanosine (substance) [SNOMED CT concept]
- Dideoxyinosine [ICD-11 Extension code]
- Dideoxyinosine [ICHI extension code]
- didanosine [SNOMED Notion]
- dideoxyinosine [SNOMED Notion]
Pharmacological action(s)
- anti-hiv agents [MeSH Descriptor]
- antimetabolites [MeSH Descriptor]
- reverse transcriptase inhibitors [MeSH Descriptor]
Record concept(s)
- NSC-612049 [MeSH concept]
- didanosine [MeSH concept]
- videx [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2',3'-dideoxy-2,8-diaza-3-deazainosine [MeSH Supplementary Concept]
- 2'-fluoro-2',3'-dideoxyinosine [MeSH Supplementary Concept]
- 2-aza-3-deaza-2',3'-dideoxyinosine [MeSH Supplementary Concept]
- 5'-O-valyldidanosine [MeSH Supplementary Concept]
- 9-(2,3-dideoxy-2-fluoro-betaD-threo-pentofuranosyl)hypoxanthine [MeSH Supplementary Concept]
- VS411 drug combination [MeSH Supplementary Concept]
- dipalmitoylphosphatidyl-2',3'-dideoxyinosine [MeSH Supplementary Concept]
- scriptene [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing didanosine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Didanosine [NCIt concept]
- Didanosine [LOINC component]
- Didanosine (substance) [SNOMED CT concept]
- Dideoxyinosine [ICD-11 Extension code]
- Product containing didanosine (medicinal product) [SNOMED CT concept]
- didanosine [ATC Code]
- didanosine [SNOMED Notion]
- dideoxyinosine [SNOMED Notion]
Validated automatic mappings to BTNT
- didanosine [ATC Code]

Keyword's position in hierarchy(ies) :

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