" /> factor viiia - CISMeF





Preferred Label : factor viiia;

MeSH definition : Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similar in structure and generation to factor Va.;

MeSH synonym : blood coagulation factor viii, activated; factor viii, activated; factor viiia, coagulation; thrombin-activated factor viii; activated factor viii; coagulation factor viiia; factor viii, thrombin-activated; factor viii, thrombin activated; Factor Eight A; Factor 8A;

CISMeF synonym : viiia, coagulation factor;

MeSH hyponym : factor VIIIa heavy chain, 200 kDa isoform; factor VIIIa heavy chain, 92 kDa isoform; factor VIIIa light chain;

MeSH CAS label : blood-coagulation factor VIIIa, procoagulant;

Registry Number MeSH : 72175-66-7;

Is substance : O;

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Keyword's position in hierarchy(ies) : arborescence

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Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similar in structure and generation to factor Va.

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05/07/2025


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