Preferred Label : gene products, rev;
MeSH definition : Trans-acting nuclear proteins whose functional expression are required for retroviral
replication. Specifically, the rev gene products are required for processing and translation
of the gag and env mRNAs, and thus rev regulates the expression of the viral structural
proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression
sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive
to the rev gene product. rev is short for regulator of virion.;
MeSH synonym : rev protein; rev gene products; gene product, rev; rev gene product;
Is substance : O;
Origin ID : D015694;
UMLS CUI : C0017282;
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Trans-acting nuclear proteins whose functional expression are required for retroviral
replication. Specifically, the rev gene products are required for processing and translation
of the gag and env mRNAs, and thus rev regulates the expression of the viral structural
proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression
sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive
to the rev gene product. rev is short for regulator of virion.
