Preferred Label : osteocalcin;
MeSH definition : Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily
in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of
bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic
acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE
and subsequent accumulation in BONE MATRIX.;
MeSH synonym : bone gamma carboxyglutamic acid protein; bone gamma-carboxyglutamic acid protein; bone gla protein; bone 4-carboxyglutamic protein; calcium-binding protein, vitamin k-dependent; gla protein, bone; vitamin k dependent bone protein; vitamin k-dependent bone protein; calcium binding protein, vitamin k dependent; 4-carboxyglutamic protein, bone; 4 carboxyglutamic protein, bone; protein, bone 4-carboxyglutamic; protein, bone gla;
MeSH CAS label : osteocalcin (human reduced), 3-de-L-tyrosine-4-de-L-glutamine-5-de-L-tryptophan-6-de-L-leucine-9-L-serine-12-L-serine-19-L-threonine-22-L-glutamine-28-L-alanine-33-L-serine-35-L-glutamine-36-L-tyrosine-38-L-leucine-39-L-lysine-40-L-threonine-43-L-lysine-45-L-isoleucine-48-L-isoleucine-49-L-threonine-49a-L-isoleucine-;
Registry Number MeSH : 104982-03-8;
Wikipedia link : https://en.wikipedia.org/wiki/Osteocalcin;
Is substance : O;
Origin ID : D015675;
UMLS CUI : C0029419;
Allowable qualifiers
- Record concept(s)
- Related MeSH Supplementary Concept(s)
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- UMLS correspondences (same concept)
Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily
in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of
bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic
acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE
and subsequent accumulation in BONE MATRIX.
