1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Preferred Label : 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine;

MeSH definition : A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.;

MeSH synonym : n-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; mptp;

MeSH CAS label : pyridine, 1,2,3,6-tetrahydro-1-methyl-4-phenyl-;

MeSH Related Number : 28289-54-5 (1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine);

Registry Number MeSH : 28289-54-5;

Codes EINECS : 248-939-7;

Is substance : O;

UNII : 9P21XSP91P;

InChIKey : PLRACCBDVIHHLZ-UHFFFAOYSA-N;

Details

Origin ID

D015632;

UMLS CUI

C0000097;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine [Substance BNPC]
Pharmacological action(s)
- dopamine agents [MeSH Descriptor]
- neurotoxins [MeSH Descriptor]
Record concept(s)
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1,2,3,6-tetrahydro-4-(4-hydroxyphenyl)-1-((3-phenyl-3-cyclohexen-1-yl)methyl)pyridine [MeSH Supplementary Concept]
- 1,2,3,6-tetrahydro-4-(p-hydroxyphenyl)-1-((3-(p-hydroxyphenyl)-3-cyclohexen-1-yl)methyl)pyridine [MeSH Supplementary Concept]
- 1,2,3,6-tetrahydro-4-phenyl-1-((3-phenyl-3-cyclohexen-1-yl)methyl)pyridine [MeSH Supplementary Concept]
- 1,3,3-trimethyl-4-phenyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-amino-4-phenyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-ethyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-ethyl-4-phenyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-methyl-3-phenyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-methyl-4-(2-(fluoromethyl)phenyl)-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-methyl-4-(3-hydroxyphenyl)-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-methyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-methyl-4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-methyl-4-(4-dimethylaminophenylethenyl)-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-methyl-4-cyclohexyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 1-methyl-4-phenyl-1,2,3,6-(tetrahydropyridine)-N-oxide [MeSH Supplementary Concept]
- 1-methyl-4-phenyl-1,2,3,6-tetrahydro-3-pyridinol [MeSH Supplementary Concept]
- 2'-fluoro-N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 3'-trifluoro-N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 4'-amino-1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 4-(4-methoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 4-benzyl-1-cyclopropyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 4-benzyl-1-methyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 4-cyclopropyl-1-methyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- 4-phenyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- N-propyl-4-phenyl-1,2,3,6-tetrahydropyridine [MeSH Supplementary Concept]
- PD 147693 [MeSH Supplementary Concept]
Related MeSH term(s)
- mptp poisoning [MeSH Descriptor]
- mptp poisoning [MeSH Descriptor]
See also (suggested by CISMeF)
- mptp poisoning [MeSH Descriptor]
Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine [Substance BNPC]
- Methylphenyltetrahydropyridine (substance) [SNOMED CT concept]
Validated automatic mappings to NTBT
- Methylphenyltetrahydropyridine (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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