Preferred Label : DNA probes;
MeSH definition : Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes,
whole chromosomes, or whole genomes) used in hybridization studies in order to identify
microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe
hybridizes with a specific mRNA, if present. Conventional techniques used for testing
for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA
hybrid-specific antibody tests. Conventional labels for the DNA probe include the
radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes
provides a specific, sensitive, rapid, and inexpensive replacement for cell culture
techniques for diagnosing infections.;
MeSH synonym : hybridization probes, dna; probes, dna; dna hybridization probes; probes, dna hybridization; DNA Probe; Probe, DNA; DNA Hybridization Probe; Hybridization Probe, DNA; Probe, DNA Hybridization;
MeSH hyponym : gene probes, DNA; whole chromosomal probes; whole genomic DNA probes; chromosomal probes; conserved gene probes; DNA Gene Probes; Probes, DNA Gene; Chromosomal Probes, Whole; Probes, Whole Chromosomal; Probes, Chromosomal; Gene Probes, Conserved; Probes, Conserved Gene;
MeSH annotation : GEN or unspecified; prefer specifics; /drug eff /ultrastruct permitted; CDNA PROBES
see DNA, COMPLEMENTARY is also available; general or unspecified; prefer specifics;
Wikipedia link : https://en.wikipedia.org/wiki/Dna probes;
Is substance : O;
Origin ID : D015342;
UMLS CUI : C0012893;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
Indexing information
Record concept(s)
See also
Semantic type(s)
UMLS correspondences (same concept)
Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes,
whole chromosomes, or whole genomes) used in hybridization studies in order to identify
microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe
hybridizes with a specific mRNA, if present. Conventional techniques used for testing
for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA
hybrid-specific antibody tests. Conventional labels for the DNA probe include the
radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes
provides a specific, sensitive, rapid, and inexpensive replacement for cell culture
techniques for diagnosing infections.