phorbol 12,13-Dibutyrate

Preferred Label : phorbol 12,13-Dibutyrate;

MeSH definition : A phorbol ester found in CROTON OIL which, in addition to being a potent skin tumor promoter, is also an effective activator of calcium-activated, phospholipid-dependent protein kinase (protein kinase C). Due to its activation of this enzyme, phorbol 12,13-dibutyrate profoundly affects many different biological systems.;

MeSH synonym : 12,13-dibutyrate, phorbol; Phorbol-12,13-Dibutyrate; phorbol 12,13 dibutyrate;

MeSH CAS label : butanoic acid, 1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa(3,4)benz(1,2-e)azulene-9,9a-diyl ester, (1aR-(1aalpha,1bbeta,4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha))-;

Registry Number MeSH : 37558-16-0;

MeSH annotation : D25-26 qualif; DF:PDBU;

Wikipedia link : https://en.wikipedia.org/wiki/Phorbol 12,13-dibutyrate;

Is substance : O;

Details

Origin ID

D015240;

UMLS CUI

C0031584;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
Pharmacological action(s)
- carcinogens [MeSH Descriptor]
Record concept(s)
- phorbol 12,13-Dibutyrate [MeSH concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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