uracil mustard

Preferred Label : uracil mustard;

MeSH definition : Nitrogen mustard derivative of URACIL. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.;

MeSH synonym : 5-(bis(2-chloroethyl)amino)-2,4-(1h,3h)pyrimidinedione; Uramustine; mustard, uracil;

MeSH CAS label : 2,4(1H,3H)-Pyrimidinedione, 5-(bis(2-chloroethyl)amino)-;

MeSH Related Number : 66-75-1 (Uracil mustard);

Registry Number MeSH : 66-75-1;

Wikipedia link : https://en.wikipedia.org/wiki/Uramustine;

Codes EINECS : 200-631-3;

Is substance : O;

UNII : W7KQ46GJ8U;

InChIKey : IDPUKCWIGUEADI-UHFFFAOYSA-N;

Details

Origin ID

D014499;

UMLS CUI

C0041920;

ATC code(s)
- uramustine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Uracil mustard [ICHI extension code]
- Uramustine [ICHI extension code]
- Uramustine [SMS substance]
- tert-butylthiol [Substance BNPC]
CISMeF manual mappings
- uracil mustard [Substance BNPC]
Currated CISMeF NLP mapping
- Uracil Mustard [NCIt concept]
- Uracil mustard [ICD-11 Extension code]
- Uramustine [ICD-11 Extension code]
- Uramustine (substance) [SNOMED CT concept]
- uracil mustard [SNOMED Notion]
Pharmacological action(s)
- antineoplastic agents, alkylating [MeSH Descriptor]
Record concept(s)
- uracil mustard [MeSH concept]
Related MeSH Supplementary Concept(s)
- chloroethylaminouracil [MeSH Supplementary Concept]
- fluorodopan [MeSH Supplementary Concept]
- nordopan glucoside [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Uracil Mustard [NCIt concept]
- Uracil mustard [ICD-11 Extension code]
- Uramustine [ICD-11 Extension code]
- Uramustine (substance) [SNOMED CT concept]
- uracil mustard [Substance BNPC]
- uracil mustard [SNOMED Notion]
- uramustine [ATC Code]
Validated automatic mappings to BTNT
- uramustine [ATC Code]

Keyword's position in hierarchy(ies) :

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