thyrotropin-releasing hormone

Preferred Label : thyrotropin-releasing hormone;

MeSH definition : A tripeptide that stimulates the release of THYROTROPIN and PROLACTIN. It is synthesized by the neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, TRH (was called TRF) stimulates the release of TSH and PRL from the ANTERIOR PITUITARY GLAND.;

MeSH synonym : protirelin; thyrotropin-releasing factor; thyrotropin releasing factor; thyrotropin releasing hormone;

CISMeF synonym : protyreline; hoechst brand of protirelin; merck, thyroliberin trh; ferring, trh; protirelin hoechst brand; thyreoliberin; rifathyroin; sanofi synthelabo brand of protirelin; trh merck, thyroliberin; 53935-32-3 (Protirelin tartrate (1:1)); protirelin abbott brand; merck brand of protirelin; protirelin merck brand; aventis brand of protirelin; protirelin aventis brand; henning berlin brand of protirelin; novartis brand of protirelin; protirelin novartis brand; ferring brand of protirelin; protirelin ferring brand; abbott brand of protirelin;

MeSH hyponym : Stimu-TSH; Abbott-38579; antepan; thypinone; TRH prem; relefact TRH; thyroliberin; protirelin tartrate (1:1); proterelin tartrate hydrate; Proterelin Tartrate; Thyrotropin-Releasing Hormone Tartrate; Thyrotropin Releasing Hormone Tartrate; TRH, Relefact; Thyroliberin TRH Merck; Prem, TRH; Hydrate, Proterelin Tartrate; Tartrate Hydrate, Proterelin; Abbott 38579; Abbott38579; Stimu TSH; StimuTSH; TRH Ferring;

MeSH CAS label : pyroGlu-His-Pro-NH2 (or 5-oxo-L-prolyl-L-histidyl-L-prolinamide);

MeSH Related Number : protirelin tartrate (1:1); 24305-27-9 (Thyrotropin-Releasing hormone); proterelin tartrate hydrate; 1N3H4TJE79; SYW8T997EQ;

Registry Number MeSH : 24305-27-9;

Related CAS MeSH : SYW8T997EQ (Protirelin tartrate (1:1)); 1N3H4TJE79 (Proterelin tartrate hydrate);

Wikipedia link : https://en.wikipedia.org/wiki/Thyrotropin-releasing hormone;

Codes EINECS : 246-143-4;

Is substance : O;

UNII : 5Y5F15120W;

InChIKey : XNSAINXGIQZQOO-SRVKXCTJSA-N;

Details

Origin ID

D013973;

UMLS CUI

C0040162;

ATC code(s)
- protirelin [ATC Code]
ATC code(s)
- protirelin [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Product containing thyrotropin releasing factor (medicinal product) [SNOMED CT concept]
- TRH Gene [NCIt concept]
- TRH wt Allele [NCIt concept]
- Thyrotropin-releasing hormone [OMIM gene]
- pre dose TRH [LOINC Challenge]
- thyrotropin releasing hormone [HGNC gene]
CISMeF manual mappings
- protirelin [Substance BNPC]
Currated CISMeF NLP mapping
- Pro-Thyrotropin-Releasing Hormone [NCIt concept]
- Prolactin releasing factor (substance) [SNOMED CT concept]
- Protirelin [ICD-11 Extension code]
- Protirelin [ICHI extension code]
- Protirelin [SMS substance]
- Protirelin [NCIt concept]
- Protirelin (substance) [SNOMED CT concept]
- Thyrotropin releasing factor [OBSOLETE LOINC component]
- Thyrotropin releasing factor (substance) [SNOMED CT concept]
- Thyrotropin releasing factor agent (substance) [Inactive SNOMED CT concept]
- Thyrotropin releasing hormone [LOINC component]
- Thyrotropin-Releasing Hormone [NCIt concept]
- Thyrotropin-releasing factor [FMA entity]
- prolactin releasing factor [SNOMED Notion]
- protirelin [ATC Code]
- protirelin [International Nonproprietary Name]
- thyrotropin releasing factor [SNOMED Notion]
- thyrotropin releasing hormone [ORDO Gene]
Exact mapping(s) to DCI
- protirelin [International Nonproprietary Name]
Indexing information
- pyroglutamyl-phenylalanyl-prolyl-N-methyl-psi(5-tetrazole) [MeSH Supplementary Concept]
Pharmacological action(s)
- hormones [MeSH Descriptor]
Record concept(s)
- Abbott-38579 [MeSH concept]
- Stimu-TSH [MeSH concept]
- TRH prem [MeSH concept]
- Thyrotropin-Releasing hormone [MeSH concept]
- antepan [MeSH concept]
- proterelin tartrate hydrate [MeSH concept]
- protirelin tartrate (1:1) [MeSH concept]
- relefact TRH [MeSH concept]
- thypinone [MeSH concept]
- thyroliberin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2-hydroxy-4-carboxybutyrylhistidylprolinamide [MeSH Supplementary Concept]
- 3-(aminocarbonyl)-1-(3-(2-(aminocarbonyl)pyrrolidin-1-yl)-3-oxo-2-(((5-oxopyrrolidin-2-yl)carbonyl)amino)propyl)pyridinium [MeSH Supplementary Concept]
- 5-oxoprolyl-2,4(5)-diiodohistidyl-prolinamide [MeSH Supplementary Concept]
- 5-oxoprolyl-4(5)-iodohistidyl-prolinamide [MeSH Supplementary Concept]
- DN 1417 [MeSH Supplementary Concept]
- Glp-asparagine-proline-D-tyrosine-D-tryptophanylamide [MeSH Supplementary Concept]
- JTP 2942 [MeSH Supplementary Concept]
- L-pGlu-(1-benzyl)-L-His-L-ProNH2 [MeSH Supplementary Concept]
- L-pyroglutamyl-L-histidyl-3,3-dimethylprolinamide [MeSH Supplementary Concept]
- N-(2-hydroxy-4-(isobutylcarbamoyl)butyryl)histidylprolinamide [MeSH Supplementary Concept]
- PR 546 [MeSH Supplementary Concept]
- TA 0910 [MeSH Supplementary Concept]
- TA 0910 acid-type [MeSH Supplementary Concept]
- TRH, 4-azidosalicylamide- [MeSH Supplementary Concept]
- amphetamine, pGlu-His- [MeSH Supplementary Concept]
- digipramine [MeSH Supplementary Concept]
- fluorescein-thyrotropin-releasing hormone [MeSH Supplementary Concept]
- glutaminyl-pyroglutamyl-glutamyl-proline amide [MeSH Supplementary Concept]
- methyl pyroglutamyl-histidyl-pipecolate [MeSH Supplementary Concept]
- montirelin [MeSH Supplementary Concept]
- orotirelin [MeSH Supplementary Concept]
- pFQ7 protein, rat [MeSH Supplementary Concept]
- pSE14 protein, rat [MeSH Supplementary Concept]
- posatirelin [MeSH Supplementary Concept]
- prepro-thyrotropin releasing hormone (160-169) [MeSH Supplementary Concept]
- prepro-thyrotropin releasing hormone (25-50) [MeSH Supplementary Concept]
- prepro-thyrotropin releasing hormone (53-74) [MeSH Supplementary Concept]
- prepro-thyrotropin-releasing hormone [MeSH Supplementary Concept]
- prepro-thyrotropin-releasing hormone (178-199) [MeSH Supplementary Concept]
- pro-thyrotropin releasing hormone [MeSH Supplementary Concept]
- protirelin, Nle(2)-Prot(3)- [MeSH Supplementary Concept]
- protirelin, Nve(2)-Prot(3)- [MeSH Supplementary Concept]
- pyro(alpha-aminoadipyl)-histidyl-prolinamide [MeSH Supplementary Concept]
- pyro(l-alpha-aminoadipyl)-L-histidyl-L-thiazolidine-4-carboxamide [MeSH Supplementary Concept]
- pyroglutamyl-((N3)-imidazolylmethyl)-histidyl-n-amylprolinamide [MeSH Supplementary Concept]
- pyroglutamyl-(2-propyl)histidyl-prolinamide [MeSH Supplementary Concept]
- pyroglutamyl-L-histidyl-L-pipecolic acid amide [MeSH Supplementary Concept]
- pyroglutamyl-glutamyl-proline amide [MeSH Supplementary Concept]
- pyroglutamyl-histidyl-3-methylprolinamide [MeSH Supplementary Concept]
- pyroglutamyl-histidyl-proline thioamide [MeSH Supplementary Concept]
- pyroglutamyl-histidyl-proline-tyramine [MeSH Supplementary Concept]
- pyroglutamyl-leucyl-prolinamide [MeSH Supplementary Concept]
- pyroglutamyl-tyrosyl-prolylamide [MeSH Supplementary Concept]
- thyroliberin N-ethylamide [MeSH Supplementary Concept]
- thyrotropin releasing hormone 5-fluoroimidazole [MeSH Supplementary Concept]
- thyrotropin releasing hormone chloromethyl ketone [MeSH Supplementary Concept]
- thyrotropin releasing hormone diazomethyl ketone [MeSH Supplementary Concept]
- thyrotropin releasing hormone, CRM45 [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, 1-(methano-Glp(2,3))- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, 1-Me- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, 2,4-MePro(3)- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, 2,4-diiodoimidazole- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, 2-diazohistidinyl- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, 2-fluoromethylimidazole- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, 2-picolyl- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, 3-Me- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, 4(5)-nitroimidazole- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, 4-fluoroimidazole- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, Gly-Lys-Arg- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, Leu(2)-Pip(3)- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, beta-(pyrazolyl-1)-Ala(2)- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, deamido- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, gly [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, linear beta-Ala- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, nVal(2)- [MeSH Supplementary Concept]
- thyrotropin-releasing hormone, pro-hydrazide- [MeSH Supplementary Concept]
See also
- receptors, thyrotropin-releasing hormone [MeSH Descriptor]
See also (suggested by CISMeF)
- thyrotropin [MeSH Descriptor]
See also inter- (CISMeF)
- Product containing protirelin (medicinal product) [SNOMED CT concept]
- Thyrotropin Releasing Hormone Measurement [NCIt concept]
- protirelin preparation [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing protirelin (medicinal product) [SNOMED CT concept]
- Product containing thyrotropin releasing factor (medicinal product) [SNOMED CT concept]
- Protirelin [NCIt concept]
- Protirelin (substance) [SNOMED CT concept]
- TRH [LOINC component]
- Thyrotropin releasing factor (substance) [SNOMED CT concept]
- Thyrotropin releasing factor agent (substance) [Inactive SNOMED CT concept]
- Thyrotropin releasing hormone [LOINC component]
- Thyrotropin-releasing factor [FMA entity]
- protirelin [ATC Code]
- protirelin [Substance BNPC]
- protirelin [International Nonproprietary Name]
- protirelin preparation [SNOMED Notion]
- thyrotropin releasing factor [SNOMED Notion]
- thyrotropin releasing hormone preparation [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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