threonine dehydratase

Preferred Label : threonine dehydratase;

MeSH definition : A pyridoxal-phosphate protein that catalyzes the deamination of THREONINE to 2-ketobutyrate and AMMONIA. The role of this enzyme can be biosynthetic or biodegradative. In the former role it supplies 2-ketobutyrate required for ISOLEUCINE biosynthesis, while in the latter it is only involved in the breakdown of threonine to supply energy. This enzyme was formerly listed as EC 4.2.1.16.;

MeSH synonym : ammonia-lyase, threonine; threonine deaminase; threonine dehydrase; dehydratase, threonine; deaminase, threonine; dehydrase, threonine; threonine ammonia-lyase; threonine ammonia lyase;

MeSH CAS label : L-Threonine hydro-lyase (deaminating);

MeSH Related Number : 9024-34-4 (CAS RN);

Registry Number MeSH : EC 4.3.1.19;

Wikipedia link : https://en.wikipedia.org/wiki/Threonine dehydratase;

Is substance : O;

UNII : EC 4.3.1.19;

Details

Origin ID

D013913;

UMLS CUI

C0040008;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Acylamino-Acid-Releasing Enzyme [NCIt concept]
- Threonine dehydratase (substance) [SNOMED CT concept]
- threonine dehydratase [SNOMED Notion]
Indexing information
- TdcA protein, E coli [MeSH Supplementary Concept]
Record concept(s)
- threonine dehydratase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ILV1 protein, S cerevisiae [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Threonine dehydratase (substance) [SNOMED CT concept]
- threonine dehydratase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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