steroid 21-hydroxylase

Preferred Label : steroid 21-hydroxylase;

MeSH definition : An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).;

MeSH synonym : cytochrome p 450 21 hydroxylase; cytochrome p-450 cyp21; progesterone 21-hydroxylase; p-450 c21, cytochrome; steroid 21-monooxygenase; 21 hydroxylase; cytochrome p-450 21-hydroxylase; cytochrome p-450 c21; cytochrome p 450 c21; cytochrome p-450(c-21); cytochrome p450c21; progesterone 21 hydroxylase; steroid 21 monooxygenase; 21-hydroxylase; cytochrome p 450 cyp21; steroid 21 hydroxylase; Steroid-21-Hydroxylase;

MeSH CAS label : steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating);

Registry Number MeSH : EC 1.14.99.10; EC 1.14.14.16;

Wikipedia link : https://en.wikipedia.org/wiki/Steroid 21-hydroxylase;

Is substance : O;

UNII : EC 1.14.14.16;

Details

Origin ID

D013255;

UMLS CUI

C0038304;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- steroid 21-Hydroxylase [MeSH concept]
Related MeSH Supplementary Concept(s)
- CYP21A1P pseudogene, human [MeSH Supplementary Concept]
- CYP21A2 protein, human [MeSH Supplementary Concept]
- CYP2C5 protein, oryctolagus cuniculus [MeSH Supplementary Concept]
- Cyp21a1 protein, mouse [MeSH Supplementary Concept]
- Cyp21a1 protein, rat [MeSH Supplementary Concept]
- Cyp2c6v1 protein, rat [MeSH Supplementary Concept]
Related MeSH term(s)
- adrenal hyperplasia, congenital [MeSH Descriptor]
See also
- adrenal hyperplasia, congenital [MeSH Descriptor]
See also (suggested by CISMeF)
- congenital adrenal hyperplasia due to 21 hydroxylase deficiency [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- 21-Hydroxylase [LOINC component]
- Steroid 21-monooxygenase (substance) [SNOMED CT concept]
- steroid 21-monooxygenase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients