steroid 11-beta-hydroxylase

Preferred Label : steroid 11-beta-hydroxylase;

MeSH definition : A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).;

MeSH synonym : cytochrome p 450 cyp11b1; steroid 11 beta monooxygenase; steroid 11 hydroxylase; steroid 11-hydroxylase; 11 beta hydroxylase; 11 beta-hydroxylase; cytochrome p-450(11 beta); steroid-11-hydroxylase; cytochrome p-450 cyp11b1; cyp11b1; steroid 11-beta-monooxygenase; cyp 11b1; cytochrome p450 11b1; steroid 11 beta hydroxylase;

MeSH CAS label : steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating);

Registry Number MeSH : EC 1.14.15.4;

Wikipedia link : https://en.wikipedia.org/wiki/Steroid 11-beta-hydroxylase;

Is substance : O;

UNII : EC 1.14.15.4;

Details

Origin ID

D013252;

UMLS CUI

C0038296;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- 4'-(pyridin-4-ylmethyl)biphenyl-3-amine [MeSH Supplementary Concept]
- 5-((5-methylpyridin-3-yl)methyl)-2-phenylpyridine [MeSH Supplementary Concept]
Record concept(s)
- steroid 11-beta-Hydroxylase [MeSH concept]
Related MeSH Supplementary Concept(s)
- Cyp11c1 protein, zebrafish [MeSH Supplementary Concept]
Related MeSH term(s)
- adrenal hyperplasia, congenital [MeSH Descriptor]
See also
- adrenal hyperplasia, congenital [MeSH Descriptor]
See also (suggested by CISMeF)
- congenital adrenal hyperplasia due to 11-Beta-hydroxylase deficiency [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cytochrome P450 CYP11B1, Mitochondrial [NCIt concept]
- Steroid 11-beta-monooxygenase (substance) [SNOMED CT concept]
- steroid 11-beta-monooxygenase [SNOMED Notion]
Validated automatic mappings to BTNT
- Cytochrome P450 CYP11B1, Mitochondrial [NCIt concept]

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