saccharopine dehydrogenases

Preferred Label : saccharopine dehydrogenases;

MeSH definition : Amine oxidoreductases that use either NAD (EC 1.5.1.7) or NADP (EC 1.5.1.8) as an acceptor to form L-LYSINE or NAD (EC 1.5.1.9) or NADP (EC 1.5.1.10) as an acceptor to form L-GLUTAMATE. Deficiency of this enzyme causes HYPERLYSINEMIAS.;

MeSH synonym : lysine-ketoglutarate reductase; dehydrogenases, saccharopine; lysine ketoglutarate reductase; reductase, lysine-ketoglutarate; Saccharopine Dehydrogenase; Dehydrogenase, Saccharopine;

CISMeF synonym : EC 1.5.1.7; EC 1.5.1.10; EC 1.5.1.-; EC 1.5.1.8; EC 1.5.1.9;

MeSH hyponym : Saccharopine Dehydrogenase (NADP , L-Lysine Forming); Saccharopine Dehydrogenase (NADP , L-Glutamate Forming); Saccharopine Dehydrogenase (NAD , L-Glutamate Forming); Saccharopine Dehydrogenase (NAD , L-Lysine Forming); Lysine-2-Oxoglutarate Reductase; Lysine 2 Oxoglutarate Reductase; Reductase, Lysine-2-Oxoglutarate;

MeSH Related Number : saccharopine dehydrogenase (NADP , L-Lysine forming); saccharopine dehydrogenase (NADP , L-Glutamate forming); saccharopine dehydrogenase (NAD , L-Glutamate forming); saccharopine dehydrogenase (NAD , L-Lysine forming); EC 1.5.1.10; EC 1.5.1.7; EC 1.5.1.8; EC 1.5.1.9;

Registry Number MeSH : EC 1.5.1.-;

Related CAS MeSH : EC 1.5.1.8 (Saccharopine dehydrogenase (NADP , L-Lysine forming)); EC 1.5.1.10 (Saccharopine dehydrogenase (NADP , L-Glutamate forming)); EC 1.5.1.9 (Saccharopine dehydrogenase (NAD , L-Glutamate forming)); EC 1.5.1.7 (Saccharopine dehydrogenase (NAD , L-Lysine forming));

MeSH annotation : /defic: consider also HYPERLYSINEMIAS;

Is substance : O;

Details

Origin ID

D012443;

UMLS CUI

C0036027;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Saccharopine Dehydrogenase (NAD+, L-Glutamate Forming) [MeSH concept]
- Saccharopine Dehydrogenase (NAD+, L-Lysine Forming) [MeSH concept]
- Saccharopine Dehydrogenase (NADP+, L-Glutamate Forming) [MeSH concept]
- Saccharopine Dehydrogenase (NADP+, L-Lysine Forming) [MeSH concept]
- saccharopine dehydrogenases [MeSH concept]
Related MeSH Supplementary Concept(s)
- AASS protein, human [MeSH Supplementary Concept]
- aass protein, mouse [MeSH Supplementary Concept]
- saccharopine dehydrogenase (NADP+, lysine-forming) [MeSH Supplementary Concept]
- saccharopine dehydrogenase (NADP, L-glutamate-forming) [MeSH Supplementary Concept]
- saccharopinuria [MeSH Supplementary Concept]
See also
- hyperlysinemias [MeSH Descriptor]
See also (suggested by CISMeF)
- saccharopinuria [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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