ribonucleoside diphosphate reductase

Preferred Label : ribonucleoside diphosphate reductase;

MeSH definition : An enzyme of the oxidoreductase class that catalyzes the formation of 2'-deoxyribonucleotides from the corresponding ribonucleotides using NADPH as the ultimate electron donor. The deoxyribonucleoside diphosphates are used in DNA synthesis. (From Dorland, 27th ed) EC 1.17.4.1.;

MeSH synonym : reductase, ribonucleoside diphosphate; diphosphate reductase, ribonucleoside;

MeSH hyponym : UDP reductase; Reductase, UDP;

MeSH CAS label : 2'-Deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase;

Registry Number MeSH : EC 1.17.4.1;

Wikipedia link : https://en.wikipedia.org/wiki/Ribonucleoside diphosphate reductase;

Is substance : O;

UNII : EC 1.17.4.1;

Details

Origin ID

D012262;

UMLS CUI

C0035545;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Ribonucleoside-Diphosphate Reductase M2 [NCIt concept]
- Ribonucleoside-diphosphate reductase (substance) [SNOMED CT concept]
- ribonucleoside-diphosphate reductase [SNOMED Notion]
Indexing information
- 2'-C-methyluridine diphosphate [MeSH Supplementary Concept]
- 2'C-methyladenosine 5'-diphosphate [MeSH Supplementary Concept]
- tezacitabine [MeSH Supplementary Concept]
Record concept(s)
- UDP reductase [MeSH concept]
- ribonucleoside diphosphate reductase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ADP reductase [MeSH Supplementary Concept]
- CDP reductase [MeSH Supplementary Concept]
- NrdA protein, E coli [MeSH Supplementary Concept]
- NrdI protein, mycoplasma gallisepticum [MeSH Supplementary Concept]
- RNR3 protein, S cerevisiae [MeSH Supplementary Concept]
- RRM1 protein, human [MeSH Supplementary Concept]
- Rnr4 protein, S cerevisiae [MeSH Supplementary Concept]
- Rrm1 protein, mouse [MeSH Supplementary Concept]
- ribonucleotide reductase M2 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Ribonucleoside-diphosphate reductase (substance) [SNOMED CT concept]
- ribonucleoside-diphosphate reductase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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