" /> receptors, LDL - CISMeF





Preferred Label : receptors, LDL;

MeSH definition : Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.;

MeSH synonym : lipoprotein ldl receptors; receptors, lipoprotein ldl; low density lipoprotein receptor; ldl receptors; receptors, lipoprotein, ldl; ldl receptors, lipoprotein; low density lipoprotein receptors; receptors, low density lipoprotein; ldl receptor; receptor, ldl;

MeSH annotation : DF: RECEPT LDL;

Is substance : O;

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Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.

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27/07/2025


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