pyrrolizidine alkaloids

Preferred Label : pyrrolizidine alkaloids;

MeSH definition : A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.;

MeSH synonym : alkaloids, pyrrolizidine; Pyrrolizidine Alkaloid; Alkaloid, Pyrrolizidine;

Related MeSH term : senecio alkaloids; Alkaloids, Senecio; Senecio Alkaloid; Alkaloid, Senecio;

Wikipedia link : https://en.wikipedia.org/wiki/Pyrrolizidine alkaloid;

Is substance : O;

Details

Origin ID

D011763;

UMLS CUI

C0034335;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Pyrrolizidine alkaloids [ICD-11 Extension code]
Record concept(s)
- pyrrolizidine alkaloids [MeSH concept]
- senecio alkaloids [MeSH concept]
Related MeSH Supplementary Concept(s)
- (3H-pyrrolizin-7-yl)methanol [MeSH Supplementary Concept]
- (hexahydro-5-oxo-1H-pyrrolizinyl-1-yl)acetic acid [MeSH Supplementary Concept]
- 1'-(4-methoxyphenyl)-2'-(furan-2-carbonyl)-1',2',5',6',7',7a'-hexahydrospiro(indoline-3,3'-pyrrolizin)-2-one [MeSH Supplementary Concept]
- 1-CHO-DHP [MeSH Supplementary Concept]
- 1-aminopyrrolizidine [MeSH Supplementary Concept]
- 1-epi-alexine [MeSH Supplementary Concept]
- 19-hydroxysenecionine [MeSH Supplementary Concept]
- 3-(3,4-dihydroxyphenyl)-8H-thieno(2,3-b)pyrrolizin-8-one [MeSH Supplementary Concept]
- 3-(3-hydroxy-4-methoxyphenyl)-8H-thieno(2,3-b)pyrrolizin-8-one [MeSH Supplementary Concept]
- 3-hydroxy-cis-nemorensic acid [MeSH Supplementary Concept]
- 4-hydroxy-nemorensic acid [MeSH Supplementary Concept]
- 5-acetamidomethyl-3-hydroxymethyl-1,6,7-trihydroxypyrrolizidine [MeSH Supplementary Concept]
- 5-chlorobohemamine C [MeSH Supplementary Concept]
- 6-azido hyacinthacine A2 [MeSH Supplementary Concept]
- 7-O-9-O-dibutyroyl-(9,9-2H2)-retronecine [MeSH Supplementary Concept]
- 7-cysteine-6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine [MeSH Supplementary Concept]
- 7-glutathione-6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine [MeSH Supplementary Concept]
- 7a-epi-hyacinthacine A1 [MeSH Supplementary Concept]
- 9-angeloylhastanecine [MeSH Supplementary Concept]
- BE 54238A [MeSH Supplementary Concept]
- BE 54238B [MeSH Supplementary Concept]
- MFM501 [MeSH Supplementary Concept]
- N-(2-(2-methoxy-6H-dipyrido(2,3-a-3,2-e)pyrrolizin-11-yl)ethyl)-2-furamide [MeSH Supplementary Concept]
- N-4-phenylphenacylheliotridanium [MeSH Supplementary Concept]
- N-acetylcysteine-6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine [MeSH Supplementary Concept]
- N-benzyl-2,2'alpha-3,3',5',6',7',7alpha,alpha'-octahydro-2-methoxycarbonylspiro(indole-3,3'-pyrrolizidine)-2-one [MeSH Supplementary Concept]
- NP 25302 [MeSH Supplementary Concept]
- PF 1018 [MeSH Supplementary Concept]
- UCS 1025A [MeSH Supplementary Concept]
- UCS1025B [MeSH Supplementary Concept]
- acetylanonamine [MeSH Supplementary Concept]
- acetylnorloline [MeSH Supplementary Concept]
- adonifoline [MeSH Supplementary Concept]
- amphorogynine A [MeSH Supplementary Concept]
- amphorogynine D [MeSH Supplementary Concept]
- anacrotine [MeSH Supplementary Concept]
- anonamine [MeSH Supplementary Concept]
- asmachilca [MeSH Supplementary Concept]
- australine [MeSH Supplementary Concept]
- axillarine [MeSH Supplementary Concept]
- bistellettazine A [MeSH Supplementary Concept]
- bistellettazine B [MeSH Supplementary Concept]
- bistellettazine C [MeSH Supplementary Concept]
- bohemamine [MeSH Supplementary Concept]
- bohemamine B [MeSH Supplementary Concept]
- bohemamine C [MeSH Supplementary Concept]
- chestnutamide [MeSH Supplementary Concept]
- clivorine [MeSH Supplementary Concept]
- cremastrine [MeSH Supplementary Concept]
- croalbinecine [MeSH Supplementary Concept]
- cyngal [MeSH Supplementary Concept]
- danaidone [MeSH Supplementary Concept]
- deacetylclivorine [MeSH Supplementary Concept]
- dehydroanacrotine [MeSH Supplementary Concept]
- dehydroretrorsine [MeSH Supplementary Concept]
- dehydrosupinidine [MeSH Supplementary Concept]
- dibohemamine D [MeSH Supplementary Concept]
- dibohemamine E [MeSH Supplementary Concept]
- dibohemamine F [MeSH Supplementary Concept]
- diplacin [MeSH Supplementary Concept]
- disenecioyldehydroretronecine [MeSH Supplementary Concept]
- echimidine [MeSH Supplementary Concept]
- echivulgarine [MeSH Supplementary Concept]
- epiaustraline [MeSH Supplementary Concept]
- erucifoline [MeSH Supplementary Concept]
- fulvine [MeSH Supplementary Concept]
- glutathione-dehydro-retronecine conjugate [MeSH Supplementary Concept]
- glutathione-jacobine conjugate [MeSH Supplementary Concept]
- hastanecine [MeSH Supplementary Concept]
- heliotridane [MeSH Supplementary Concept]
- heliotrine [MeSH Supplementary Concept]
- heliotrine N-oxide [MeSH Supplementary Concept]
- hexahydro-1H-pyrrolizin-1-ylmethyl 1-methyl-1H-indole-3-carboxylate [MeSH Supplementary Concept]
- hyacinthacine A1 [MeSH Supplementary Concept]
- hyacinthacine A2 [MeSH Supplementary Concept]
- hyacinthacine A3 [MeSH Supplementary Concept]
- hyacinthacine B3 [MeSH Supplementary Concept]
- hyacinthacine B4 [MeSH Supplementary Concept]
- hyacinthacine B5 [MeSH Supplementary Concept]
- hyacinthacine B7 [MeSH Supplementary Concept]
- hyacinthacine C1 [MeSH Supplementary Concept]
- hyacinthacine C5 [MeSH Supplementary Concept]
- hydroxydanaidal [MeSH Supplementary Concept]
- hydroxysenkirkine [MeSH Supplementary Concept]
- indicine [MeSH Supplementary Concept]
- indicine-N-oxide [MeSH Supplementary Concept]
- intermedine [MeSH Supplementary Concept]
- isatidine [MeSH Supplementary Concept]
- isoline [MeSH Supplementary Concept]
- isoretronecanol [MeSH Supplementary Concept]
- jacobine [MeSH Supplementary Concept]
- laburnine [MeSH Supplementary Concept]
- lasiocarpine [MeSH Supplementary Concept]
- latifoline [MeSH Supplementary Concept]
- lindelofine-N-oxide [MeSH Supplementary Concept]
- megalanthonine [MeSH Supplementary Concept]
- nemorensic acid [MeSH Supplementary Concept]
- nervosine VII [MeSH Supplementary Concept]
- osyrisine [MeSH Supplementary Concept]
- otonecine [MeSH Supplementary Concept]
- otosenine [MeSH Supplementary Concept]
- penibruguieramine A [MeSH Supplementary Concept]
- penicinoline [MeSH Supplementary Concept]
- platyphylline [MeSH Supplementary Concept]
- pyrrolam A [MeSH Supplementary Concept]
- retronecine [MeSH Supplementary Concept]
- retrorsine [MeSH Supplementary Concept]
- riddelliine [MeSH Supplementary Concept]
- riddelliine N-oxide [MeSH Supplementary Concept]
- rosmarinecine [MeSH Supplementary Concept]
- sarracine [MeSH Supplementary Concept]
- senaetnine [MeSH Supplementary Concept]
- senecion [MeSH Supplementary Concept]
- senecionine [MeSH Supplementary Concept]
- senecionine N-oxide [MeSH Supplementary Concept]
- seneciphylline [MeSH Supplementary Concept]
- seneciphyllinine [MeSH Supplementary Concept]
- senesionine [MeSH Supplementary Concept]
- senkirkine [MeSH Supplementary Concept]
- spiropyrrolizidine oxime 222 [MeSH Supplementary Concept]
- spiropyrrolizidine oxime 236 [MeSH Supplementary Concept]
- spithioneine A [MeSH Supplementary Concept]
- spithioneine B [MeSH Supplementary Concept]
- strigosine [MeSH Supplementary Concept]
- supinidine [MeSH Supplementary Concept]
- swazine [MeSH Supplementary Concept]
- symlandine [MeSH Supplementary Concept]
- symphytine [MeSH Supplementary Concept]
- synthanecine A-bis(N-ethylcarbamate) [MeSH Supplementary Concept]
- talarotoxin [MeSH Supplementary Concept]
- thesinine-O-4'-alpha-rhamnoside [MeSH Supplementary Concept]
- trachelanthamidine [MeSH Supplementary Concept]
- turneforcidine [MeSH Supplementary Concept]
- xenovenine [MeSH Supplementary Concept]
See also
- senecio [MeSH Descriptor]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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