Purine-Nucleoside phosphorylase

Preferred Label : Purine-Nucleoside phosphorylase;

MeSH definition : An enzyme that catalyzes the reaction between a purine nucleoside and orthophosphate to form a free purine plus ribose-5-phosphate. EC 2.4.2.1.;

MeSH synonym : phosphorylase, inosine; purine nucleoside phosphorylases; nucleoside phosphorylases, purine; phosphorylases, purine nucleoside; phosphorylase, purine-nucleoside; inosine phosphorylase; purine nucleoside phosphorylase;

MeSH hyponym : nicotinamide riboside phosphorylase; Phosphorylase, Nicotinamide Riboside; Riboside Phosphorylase, Nicotinamide;

MeSH CAS label : purine-nucleoside:orthophosphate ribosyltransferase;

MeSH Related Number : 9030-21-1 (CAS RN);

Registry Number MeSH : EC 2.4.2.1;

Wikipedia link : https://en.wikipedia.org/wiki/Purine nucleoside phosphorylase;

Is substance : O;

UNII : EC 2.4.2.1;

Details

Origin ID

D011683;

UMLS CUI

C0034135;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Fumarate Hydratase, Mitochondrial [NCIt concept]
- Immunodeficiency due to purine nucleoside phosphorylase deficiency [ICD-11 More detail]
- Purine nucleoside phosphorylase [OMIM gene]
- purine nucleoside phosphorylase [HGNC gene]
- purine nucleoside phosphorylase [ORDO Gene]
CISMeF manual mappings
- Substance with purine nucleoside phosphorylase inhibitor mechanism of action (substance) [SNOMED CT concept]
Indexing information
- 1,1-difluoro-2-(tetrahydro-3-furanyl)ethylphosphonic acid [MeSH Supplementary Concept]
- 1-((8-aza-9-deazahypoxanthin-9-yl)methyl)-3-hydroxy-4-hydroxymethylpyrrolidine [MeSH Supplementary Concept]
- 1-((9-deazaguanin-9-yl)methyl)-3-hydroxy-4-hydroxymethylpyrrolidine [MeSH Supplementary Concept]
- 1-((9-deazahypoxanthin-9-yl)methyl)-3-hydroxy-4-hydroxymethylpyrrolidine [MeSH Supplementary Concept]
- 2,5-diaminothiazolo(4,5-d)pyrimidin-7-(6H)-one [MeSH Supplementary Concept]
- 2,5-diaminothiazolo(5,4-d)pyrimidin-7(6H)-one [MeSH Supplementary Concept]
- 2-(4-amino-5H-pyrrolo-(3,2-d)pyrimidin-7-yl)-5-methylsulfanylmethylpyrrolidin-3,4-diol [MeSH Supplementary Concept]
- 3-(2-amino-4-oxo-3H,5H-pyrrolo(3,2-d)pyrimidin-7-yl)-3-(3-chlorophenyl)propanoic acid [MeSH Supplementary Concept]
- 3-(guanin-9-yl)pyrrolidin-N-ylcarbonylphosphonic acid [MeSH Supplementary Concept]
- 4'-deaza-1'-aza-2'-deoxy-1'-(9-methylene)-immucillin A [MeSH Supplementary Concept]
- 4'-deaza-1'-aza-2'-deoxy-1'-(9-methylene)immucillin G [MeSH Supplementary Concept]
- 4-(guanin-9-yl)-3-hydroxypyrrolidin-1-N-ylcarbonylphosphonic acid [MeSH Supplementary Concept]
- 5'-chloro-5'-deoxy-9-deazaadenosine [MeSH Supplementary Concept]
- 5'-deoxy-5'-iodo-9-deazainosine [MeSH Supplementary Concept]
- 5'-methylthio-5'-deoxy-9-deazaadenosine [MeSH Supplementary Concept]
- 5-amino-1-ribofuranosyl-1,2,4-triazole-3-carboxamidine [MeSH Supplementary Concept]
- 8-amino-2'-nordeoxyguanosine [MeSH Supplementary Concept]
- 8-amino-3-benzylhypoxanthine [MeSH Supplementary Concept]
- 8-amino-9-(2-thienylmethyl)guanine [MeSH Supplementary Concept]
- 8-amino-9-benzylguanine [MeSH Supplementary Concept]
- 8-aminoguanine [MeSH Supplementary Concept]
- 8-aminoguanosine [MeSH Supplementary Concept]
- 9-(3,3-dimethyl-5-phosphonopentyl)guanine [MeSH Supplementary Concept]
- 9-benzyl-9-deazaguanine [MeSH Supplementary Concept]
- 9-deaza-9-(3-thienylmethyl)guanine [MeSH Supplementary Concept]
- CI 972 [MeSH Supplementary Concept]
- DADMe-immucillin H [MeSH Supplementary Concept]
- MT-immucillin H [MeSH Supplementary Concept]
- forodesine [MeSH Supplementary Concept]
- galidesivir [MeSH Supplementary Concept]
- immucillin G [MeSH Supplementary Concept]
- taribavirin [MeSH Supplementary Concept]
Record concept(s)
- Purine-Nucleoside phosphorylase [MeSH concept]
- nicotinamide riboside phosphorylase [MeSH concept]
Related MeSH Supplementary Concept(s)
- 5'-methylthioadenosine phosphorylase [MeSH Supplementary Concept]
- MTAN1 protein, arabidopsis [MeSH Supplementary Concept]
- MTAN2 protein, arabidopsis [MeSH Supplementary Concept]
- adenosine phosphorylase [MeSH Supplementary Concept]
- inosine phosphorylase deficiency, immune defect due to [MeSH Supplementary Concept]
- purine nucleoside phosphorylase deficiency [MeSH Supplementary Concept]
- xanthosine phosphorylase [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Purine nucleoside phosphorylase [LOINC component]
- Purine-nucleoside phosphorylase (substance) [SNOMED CT concept]
- purine-nucleoside phosphorylase [SNOMED Notion]

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