prions - CISMeF

Preferred Label : prions;

MeSH definition : Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.;

MeSH synonym : Prion;

MeSH hyponym : mink encephalopathy virus; Encephalopathy Virus, Mink;

MeSH annotation : /pathogen permitted;

Wikipedia link : https://en.wikipedia.org/wiki/Prion;

Is substance : O;

Details

Origin ID

D011328;

UMLS CUI

C0033164;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pathogenicity [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Prion protein [LOINC component]
Record concept(s)
- mink encephalopathy virus [MeSH concept]
- prions [MeSH concept]
Related MeSH Supplementary Concept(s)
- (ctm)PrP [MeSH Supplementary Concept]
- New1 protein, S cerevisiae [MeSH Supplementary Concept]
- PQN-47 protein, C elegans [MeSH Supplementary Concept]
- PRND protein, human [MeSH Supplementary Concept]
- PRNP protein, human [MeSH Supplementary Concept]
- RNQ1 protein, S cerevisiae [MeSH Supplementary Concept]
- Sup35 protein, candida albicans [MeSH Supplementary Concept]
- URE2 protein, S cerevisiae [MeSH Supplementary Concept]
- miniprion protein PrP106, mouse [MeSH Supplementary Concept]
- prion protein (105-132) [MeSH Supplementary Concept]
- prion protein (106-126) [MeSH Supplementary Concept]
- prion protein (113-127) [MeSH Supplementary Concept]
- prion protein (113-132) [MeSH Supplementary Concept]
- prion protein (118-135) [MeSH Supplementary Concept]
- prion protein (121-231) [MeSH Supplementary Concept]
- prion protein (125-228), human [MeSH Supplementary Concept]
- prion protein (127-147) [MeSH Supplementary Concept]
- prion protein (131-188) [MeSH Supplementary Concept]
- prion protein (143-158) [MeSH Supplementary Concept]
- prion protein (198-227) [MeSH Supplementary Concept]
- prion protein (214-226) [MeSH Supplementary Concept]
- prion protein (23-110) [MeSH Supplementary Concept]
- prion protein (23-231) [MeSH Supplementary Concept]
- prion protein (23-98) [MeSH Supplementary Concept]
- prion protein (59-91) [MeSH Supplementary Concept]
- prion protein (60-67) [MeSH Supplementary Concept]
- prion protein (76-114), human [MeSH Supplementary Concept]
- prion protein (82-146) [MeSH Supplementary Concept]
- prion protein (90-231) [MeSH Supplementary Concept]
- prion protein (91-231), human [MeSH Supplementary Concept]
- prnd protein, mouse [MeSH Supplementary Concept]
- prnp protein, leucyl(101), mouse [MeSH Supplementary Concept]
- prnp protein, mouse [MeSH Supplementary Concept]
See also
- scrapie [MeSH Descriptor]
See also (suggested by CISMeF)
- prion diseases [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
UMLS correspondences (same concept)
- Prion [ICD-11 Extension code]
- Prion (organism) [SNOMED CT concept]
- prion [ICPS Descriptor]
- prion, nos [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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