poly I-C - CISMeF

Preferred Label : poly I-C;

MeSH definition : Interferon inducer consisting of a synthetic, mismatched double-stranded RNA. The polymer is made of one strand each of polyinosinic acid and polycytidylic acid.;

MeSH synonym : polyribose inosin-cytidil; inosin-cytidil, polyribose; polyribose inosin cytidil; poly(ri).poly(rc); polyinosinic-polycytidylic acid; polyinosinic polycytidylic acid; poly I C; Poly(I-C); Polyriboinosinic-Polyribocytidylic Acid; Polyriboinosinic Polyribocytidylic Acid; Polyinosinic-Polycytidylic Acid (High MW);

Wikipedia automatic translation : Polyinosinic:polycytidylic acid;

MeSH CAS label : 5'-Inosinic acid, homopolymer, complex with 5'-cytidylic acid homopolymer (1:1);

MeSH Related Number : 24939-03-5;

Registry Number MeSH : 24939-03-5;

MeSH annotation : an interferon inducer; do not confuse with POLY I; do not confuse with POLY I;

Wikipedia link : https://en.wikipedia.org/wiki/Polyinosinic:polycytidylic acid;

Is substance : O;

UNII : O84C90HH2L;

Details

Origin ID

D011070;

UMLS CUI

C0032414;

ATC code(s)
- poly i:c [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Polyinosinic-polycytidylic acid [COVID-19 Thesaurus concept]
Currated CISMeF NLP mapping
- Poly IC [NCIt concept]
Indexing information
- poly(I):poly(C)-binding, 50 kDa protein, mouse [MeSH Supplementary Concept]
Pharmacological action(s)
- antiviral agents [MeSH Descriptor]
- interferon inducers [MeSH Descriptor]
Record concept(s)
- poly I-C [MeSH concept]
Related MeSH Supplementary Concept(s)
- BO-112 [MeSH Supplementary Concept]
- PIKA adjuvant [MeSH Supplementary Concept]
- poly I-5-mercapto-poly C [MeSH Supplementary Concept]
- poly IC-polylysine carboxymethyl dextran [MeSH Supplementary Concept]
- poly ICL [MeSH Supplementary Concept]
- poly ICLC [MeSH Supplementary Concept]
- poly(2'-azido-2'-deoxyinosinic acid).polycytidylic acid [MeSH Supplementary Concept]
- poly(2'-chloro-2'-deoxyinosinic acid).polycytidylic acid [MeSH Supplementary Concept]
- poly(2'-fluoro-2'-deoxyinosinic acid).polycytidylic acid [MeSH Supplementary Concept]
- poly(G,I).poly(C) [MeSH Supplementary Concept]
- poly(I).poly(c12,U) [MeSH Supplementary Concept]
- poly(I,8-azidoI).poly(C) [MeSH Supplementary Concept]
- poly(I,8-azidoI).poly(C12,U) [MeSH Supplementary Concept]
- retrogen D [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Poly IC [NCIt concept]
- poly i:c [ATC Code]
Validated automatic mappings to BTNT
- poly i:c [ATC Code]

Keyword's position in hierarchy(ies) :

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