orotate phosphoribosyltransferase

Preferred Label : orotate phosphoribosyltransferase;

MeSH definition : The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the course of pyrimidine nucleotide biosynthesis. EC 2.4.2.10.;

MeSH synonym : orotidylic acid phosphorylase; orotidine 5' phosphate pyrophosphorylase; phosphohydrolase, orotidine-5'-monophosphate; orotidine 5' monophosphate phosphohydrolase; orotidine-5'-phosphate pyrophosphorylase; pyrophosphorylase, orotidine-5'-phosphate; ompase; orotidine-5'-monophosphate phosphohydrolase; phosphoribosyltransferase, orotate; phosphorylase, orotidylic acid;

MeSH CAS label : Orotidine-5'-phosphate:pyrophosphate phospho-alpha-D-ribosyltransferase;

MeSH Related Number : 9030-25-5 (CAS RN);

Registry Number MeSH : EC 2.4.2.10;

MeSH annotation : /defic: consider also OROTIC ACID /urine (IM) PURINE-PYRIMIDINE METABOLISM, INBORN ERRORS (IM);

Is substance : O;

UNII : EC 2.4.2.10;

Details

Origin ID

D009962;

UMLS CUI

C0029298;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- orotate phosphoribosyltransferase [MeSH concept]
Related MeSH Supplementary Concept(s)
- orotic aciduria II [MeSH Supplementary Concept]
- oroticaciduria 1 [MeSH Supplementary Concept]
- uridine 5'-monophosphate synthase [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Orotate phosphoribosyltransferase [LOINC component]
- Orotate phosphoribosyltransferase (substance) [SNOMED CT concept]
- orotate phosphoribosyltransferase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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