masoprocol - CISMeF

Preferred Label : masoprocol;

MeSH definition : A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.;

MeSH synonym : dihydronorguaiaretic acid; nordihydroguaiaretic acid, (R*,S*)-Isomer; meso-Nordihydroguaiaretic acid; (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol; nordihydroguaiaretic acid; acid, meso-Nordihydroguaiaretic; meso nordihydroguaiaretic acid;

CISMeF synonym : 27686-84-6 (Masoprocol); 4,4'-(2,3 dimethyl-1,4-butanediyl)bis(1,2-benzenediol);

MeSH hyponym : actinex;

MeSH CAS label : 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-;

MeSH Related Number : 27686-84-6 (Nordihydroguaiaretic acid (R*,S*)-isomer); 500-38-9 (Nordihydroguaiaretic acid);

Registry Number MeSH : 500-38-9;

MeSH annotation : DF: NDGA;

Codes EINECS : 207-903-0;

Is substance : O;

UNII : 7BO8G1BYQU;

InChIKey : HCZKYJDFEPMADG-TXEJJXNPSA-N;

Details

Origin ID

D009637;

UMLS CUI

C0733397;

ATC code(s)
- masoprocol [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Masoprocol [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Masoprocol [NCIt concept]
- Masoprocol (substance) [SNOMED CT concept]
- masoprocol [Substance BNPC]
Pharmacological action(s)
- antioxidants [MeSH Descriptor]
- cyclooxygenase inhibitors [MeSH Descriptor]
- lipoxygenase inhibitors [MeSH Descriptor]
Record concept(s)
- actinex [MeSH concept]
- masoprocol [MeSH concept]
Related MeSH Supplementary Concept(s)
- heminordihydroguaiaretic acid [MeSH Supplementary Concept]
- maltose-tri-O-methyl nordihydroguaiaretic acid [MeSH Supplementary Concept]
- nordy [MeSH Supplementary Concept]
- terameprocol [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing masoprocol (medicinal product) [SNOMED CT concept]
- nordihydroguaiaretic acid [Substance BNPC]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Masoprocol [NCIt concept]
- Masoprocol (substance) [SNOMED CT concept]
- Product containing masoprocol (medicinal product) [SNOMED CT concept]
- masoprocol [ATC Code]
- nordihydroguaiaretic acid [Substance BNPC]
Validated automatic mappings to BTNT
- masoprocol [ATC Code]

Keyword's position in hierarchy(ies) :

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