monoamine oxidase

Preferred Label : monoamine oxidase;

MeSH definition : An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4.;

MeSH synonym : amine oxidase (flavin-containing); oxidase, tyramine; oxidase, monoamine; tyramine oxidase; mao;

MeSH hyponym : type A monoamine oxidase; monoamine oxidase B; MAO-A; MAO A; Monoamine Oxidase A; MAO-B; MAO B; Type B Monoamine Oxidase;

MeSH CAS label : amine:oxygen oxidoreductase (deaminating) (flavin-containing);

MeSH Related Number : 9001-66-5 (CAS RN);

Registry Number MeSH : EC 1.4.3.4;

Wikipedia link : https://en.wikipedia.org/wiki/Monoamine oxidase;

Is substance : O;

UNII : EC 1.4.3.4;

Details

Origin ID

D008995;

UMLS CUI

C0026454;

ATC code(s)
- mao inhibitors [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Amine oxidase (flavin-containing) (substance) [SNOMED CT concept]
- Monoamine oxidase [LOINC component]
- amine oxidase (flavin-containing) [SNOMED Notion]
False automatic mappings
- Methaqualone [NCIt concept]
Indexing information
- 2-fluoro-2-phenylcyclopropylamine [MeSH Supplementary Concept]
- 3-(3-nitrophenyl)-9H-indeno(1,2-e)(1,2,4)triazin-9-one [MeSH Supplementary Concept]
- 3-hydroxy-2-oxoindole [MeSH Supplementary Concept]
- 3-methoxymethyl-7-(4,4,4-trifluorobutoxy)-3,3a,4,5-tetrahydro-1,3-oxazolo(3,4-a)quinolin-1-one [MeSH Supplementary Concept]
- M32 compound [MeSH Supplementary Concept]
- N-(2-benzyl),N-(1-methylpyrrol-2-ylmethyl)amine [MeSH Supplementary Concept]
- N-methyl,N-(benzyl),N-(pyrrol-2-ylmethyl)amine [MeSH Supplementary Concept]
- scopoletin peroxidase [MeSH Supplementary Concept]
Record concept(s)
- monoamine oxidase [MeSH concept]
- monoamine oxidase B [MeSH concept]
- type A monoamine oxidase [MeSH concept]
Related MeSH Supplementary Concept(s)
- KB220Z [MeSH Supplementary Concept]
- MAOB protein, human [MeSH Supplementary Concept]
- TynA protein, E coli [MeSH Supplementary Concept]
- brunner syndrome [MeSH Supplementary Concept]
- monoamine oxidase A, human [MeSH Supplementary Concept]
- renalase [MeSH Supplementary Concept]
Related MeSH term(s)
- monoamine oxidase inhibitors [MeSH Descriptor]
See also (suggested by CISMeF)
- monoamine oxidase inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Amine oxidase (flavin-containing) (substance) [SNOMED CT concept]
- Monoamine oxidase [LOINC component]
- amine oxidase (flavin-containing) [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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