misonidazole - CISMeF

Preferred Label : misonidazole;

MeSH definition : A nitroimidazole that sensitizes normally radio-resistant hypoxic cells to radiation. It may also be directly cytotoxic to hypoxic cells and has been proposed as an antineoplastic.;

MeSH synonym : alpha-(methoxymethyl)-2-nitro-1h-imidazole-1-ethanol;

MeSH hyponym : ro 07-0582; Ro 07 0582; Ro 070582; Ro 7-0582; Ro 7 0582; Ro 70582;

MeSH CAS label : 1H-Imidazole-1-ethanol, alpha-(methoxymethyl)-2-nitro-;

MeSH Related Number : 13551-87-6 (Misonidazole);

Registry Number MeSH : 13551-87-6;

Wikipedia link : https://en.wikipedia.org/wiki/Misonidazole;

Codes EINECS : 236-931-6;

Is substance : O;

UNII : 8FE7LTN8XE;

InChIKey : OBBCSXFCDPPXOL-UHFFFAOYSA-N;

Details

Origin ID

D008920;

UMLS CUI

C0026218;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Misonidazole [ICHI extension code]
CISMeF manual mappings
- misonidazole [Substance BNPC]
Currated CISMeF NLP mapping
- Misonidazole [ICD-11 Extension code]
- Misonidazole [NCIt concept]
- Misonidazole (substance) [SNOMED CT concept]
Pharmacological action(s)
- antineoplastic agents [MeSH Descriptor]
- antiprotozoal agents [MeSH Descriptor]
- radiation-sensitizing agents [MeSH Descriptor]
Record concept(s)
- misonidazole [MeSH concept]
- ro 07-0582 [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-(2-nitro-1-imidazoly)-3-(2,3-dimethylaziridino)-2-propanol [MeSH Supplementary Concept]
- 1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol [MeSH Supplementary Concept]
- 1-(2-nitro-1-imidazoyl)-3-(2,2,2-trifluoroethoxy)-2-propanol [MeSH Supplementary Concept]
- 1-(4'-hydroxy-2'-butenoxy)methyl-2-nitroimidazole [MeSH Supplementary Concept]
- 2,2'-azomisonidazole [MeSH Supplementary Concept]
- 2,2'-azoxymisonidazole [MeSH Supplementary Concept]
- 2-amino-4,5-dihydro-4,5-dihydroxy-1-(2'-hydroxy-3'-methoxy-1'-propyl)imidazole [MeSH Supplementary Concept]
- 2-aminomisonidazole [MeSH Supplementary Concept]
- 2-hydroxyaminomisonidazole [MeSH Supplementary Concept]
- 4,5-dimethylmisonidazole [MeSH Supplementary Concept]
- 4-bromomisonidazole [MeSH Supplementary Concept]
- 5-(2-nitroimidazolyl)-4-hydroxy-1-iodopent-1-ene [MeSH Supplementary Concept]
- RB 7040 [MeSH Supplementary Concept]
- RK 29 [MeSH Supplementary Concept]
- RSU 1131 [MeSH Supplementary Concept]
- RSU 1137 [MeSH Supplementary Concept]
- RSU 1172 [MeSH Supplementary Concept]
- desmethylmisonidazole [MeSH Supplementary Concept]
- fluoromisonidazole [MeSH Supplementary Concept]
- misonidazole glucuronide [MeSH Supplementary Concept]
- misonidazole-glutathione conjugate [MeSH Supplementary Concept]
- ro 07-1902 [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Misonidazole [ICD-11 Extension code]
- Misonidazole [NCIt concept]
- Misonidazole (substance) [SNOMED CT concept]
- misonidazole [Substance BNPC]

Keyword's position in hierarchy(ies) :

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