metyrapone - CISMeF

Preferred Label : metyrapone;

MeSH definition : An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.;

MeSH synonym : methopyrapone; methbipyranone;

CISMeF synonym : 4885, SU; novartis brand of metyrapone; metyrapone novartis brand; alliance brand of metyrapone; metyrapone alliance brand;

DeCS synonym : M topirone;

MeSH hyponym : métopirone; metopirone; SU 4885; Metopiron;

MeSH CAS label : 1-Propanone, 2-methyl-1,2-di-3-pyridinyl-;

MeSH Related Number : 54-36-4 (Metyrapone);

Registry Number MeSH : 54-36-4;

Wikipedia link : https://en.wikipedia.org/wiki/Metyrapone;

Codes EINECS : 200-206-2;

Is substance : O;

UNII : ZS9KD92H6V;

InChIKey : FJLBFSROUSIWMA-UHFFFAOYSA-N;

Details

Origin ID

D008797;

UMLS CUI

C0025876;

ATC code(s)
- metyrapone [ATC Code]
ATC code(s)
- metyrapone [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- metyrapone [Substance BNPC]
Currated CISMeF NLP mapping
- Metyrapone [ICD-11 Extension code]
- Metyrapone [ICHI extension code]
- Metyrapone [NCIt concept]
- Metyrapone (substance) [SNOMED CT concept]
- metyraPONE [LOINC component]
- metyraPONE [LOINC Challenge]
- metyrapone [SNOMED Notion]
Pharmacological action(s)
- antimetabolites [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
Record concept(s)
- SU 4885 [MeSH concept]
- metopirone [MeSH concept]
- metyrapone [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2-bromophenylmetyrapone [MeSH Supplementary Concept]
- 2-hydroxyphenylmetyrapone [MeSH Supplementary Concept]
- 2-iodophenylmetyrapone [MeSH Supplementary Concept]
- 2-methoxyphenylmetyrapone [MeSH Supplementary Concept]
- 2-methoxyphenylmetyrapone N-oxide [MeSH Supplementary Concept]
- 2-methyl-1,2-diphenyl-1-propanone [MeSH Supplementary Concept]
- 2-methyl-1-(3-(6-oxopyridyl))-2-(3-pyridyl)-1-propanone [MeSH Supplementary Concept]
- 2-methyl-1-phenyl-2-(3-pyridinyl)-1-propanone [MeSH Supplementary Concept]
- NKI 42255 [MeSH Supplementary Concept]
- metyrapol [MeSH Supplementary Concept]
- metyrapone N-oxide [MeSH Supplementary Concept]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Metyrapone [Pharmacological Root]
- Metyrapone [ICD-11 Extension code]
- Metyrapone [NCIt concept]
- Metyrapone (substance) [SNOMED CT concept]
- Product containing metyrapone (medicinal product) [SNOMED CT concept]
- metyraPONE [LOINC Challenge]
- metyraPONE [LOINC component]
- metyrapone [ATC Code]
- metyrapone [Substance BNPC]
- metyrapone [SNOMED Notion]
Used as substance for
- Metyrapone [Pharmacological Root]
Validated automatic mappings to BTNT
- metyrapone [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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