lymphocyte activation

Preferred Label : lymphocyte activation;

MeSH definition : Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.;

MeSH synonym : transformation, lymphocyte; activation, lymphocyte; lymphocyte transformation; stimulation, lymphocyte; blast transformation; blastogenesis; lymphocyte stimulation; transformation, lymphoblast; lymphoblast transformation; transformation, blast;

MeSH annotation : lymphocyte transformation test goes here but do not index under specific agent inducing transformation unless particularly discussed; do not use for neoplastic transformation of lymphocytes ( CELL TRANSFORMATION, NEOPLASTIC) or viral transformation of lymphocytes ( CELL TRANSFORMATION, VIRAL); blast transformation in chronic myelogenous leukemia does not go here: index BLAST CRISIS; DF: LYMPHOCYTE TRANSFORM; lymphocyte transformation test goes here but do not index under specific agent inducing transformation unless particularly discussed; do not use for neoplastic transformation of lymphocytes ( CELL TRANSFORMATION, NEOPLASTIC) or viral transformation of lymphocytes ( CELL TRANSFORMATION, VIRAL); blast transformation in chronic myelogenous leukemia does not go here: index BLAST CRISIS;

Details

Origin ID

D008213;

UMLS CUI

C0024262;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Activated Lymphocyte [NCIt concept]
- Activated Lymphocytes Measurement [NCIt concept]
- lymphocyte costimulation [GO term]
Currated CISMeF NLP mapping
- Lymphocyte Activation Process [NCIt concept]
- lymphocyte activation [GO term]
Indexing information
- CD100 antigen [MeSH Supplementary Concept]
- CD69 antigen [MeSH Supplementary Concept]
- GP 40-80 glycoprotein, human [MeSH Supplementary Concept]
- MLR3 activation antigen [MeSH Supplementary Concept]
- concanavalin A-induced helper factors [MeSH Supplementary Concept]
- lymphocyte proliferation potentiating factors [MeSH Supplementary Concept]
- nordimaprit [MeSH Supplementary Concept]
- thymocyte-activating factor, fibroblasts [MeSH Supplementary Concept]
Record concept(s)
- lymphocyte activation [MeSH concept]
See also
- Lymphocyte Activation Gene 3 Protein [MeSH Descriptor]
- antigen-presenting cells [MeSH Descriptor]
- blast crisis [MeSH Descriptor]
See also (suggested by CISMeF)
- minor lymphocyte stimulatory antigens [MeSH Descriptor]
Semantic type(s)
- Cell Function [UMLS semantic type]
UMLS correspondences (same concept)
- Lymphocyte Activation Process [NCIt concept]
- lymphocyte activation [GO term]

Keyword's position in hierarchy(ies) :

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