Preferred Label : leucyl aminopeptidase;
MeSH definition : A zinc containing enzyme of the hydrolase class that catalyzes the removal of the
N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine
residues but not those with N-terminal lysine or arginine residues. This occurs in
tissue cell cytosol, with high activity in the duodenum, liver, and kidney. The activity
of this enzyme is commonly assayed using a leucine arylamide chromogenic substrate
such as leucyl beta-naphthylamide.;
MeSH synonym : aminopeptidase, zinc-manganese-leucine; cytosol aminopeptidase; l-leucylnaphthylamidase; zinc manganese leucine aminopeptidase; aminopeptidase, leucyl; zinc-manganese-leucine aminopeptidase; aminopeptidase, cytosol; leucine aminopeptidase; aminopeptidase, leucine; peptidase s;
CISMeF synonym : s, peptidase;
MeSH hyponym : methoxyleucine aminopeptidase; Aminopeptidase, Methoxyleucine;
Registry Number MeSH : EC 3.4.11.1;
Wikipedia link : https://en.wikipedia.org/wiki/Leucyl aminopeptidase;
Is substance : O;
UNII : EC 3.4.11.1;
Origin ID : D007931;
UMLS CUI : C0023402;
Allowable qualifiers
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A zinc containing enzyme of the hydrolase class that catalyzes the removal of the
N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine
residues but not those with N-terminal lysine or arginine residues. This occurs in
tissue cell cytosol, with high activity in the duodenum, liver, and kidney. The activity
of this enzyme is commonly assayed using a leucine arylamide chromogenic substrate
such as leucyl beta-naphthylamide.
