killer cells, natural

Preferred Label : killer cells, natural;

MeSH definition : Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.;

MeSH synonym : cell, nk; nk cell; cells, natural killer; cells, nk; natural killer cells; cell, natural killer; killer cell, natural; natural killer cell; nk cells;

MeSH annotation : do not confuse with NATURAL KILLER T-CELLS; if subpopulations are discussed, coordinate IM with LYMPHOCYTE SUBSETS (IM);

Wikipedia link : https://en.wikipedia.org/wiki/Natural killer cell;

Details

Origin ID

D007694;

UMLS CUI

C0022688;

Allowable qualifiers
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- cytology [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- enzymology [MeSH Qualifier]
- immunology [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- microbiology [MeSH Qualifier]
- parasitology [MeSH Qualifier]
- pathology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- transplantation [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- virology [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Natural Killer Cell Count [NCIt concept]
- Natural Killer T-Cell [NCIt concept]
- natural killer cell [COVID-19 Thesaurus concept]
Currated CISMeF NLP mapping
- Natural Killer Cell [NCIt concept]
- Natural killer cell [FMA entity]
- Natural killer cell (cell) [SNOMED CT concept]
Indexing information
- B-NK1 protein, gallus gallus [MeSH Supplementary Concept]
- HCST protein, human [MeSH Supplementary Concept]
- KIR2DS2 protein, human [MeSH Supplementary Concept]
- KIR2DS4 protein, human [MeSH Supplementary Concept]
- Klrb1a protein, rat [MeSH Supplementary Concept]
- Klrb1b protein, rat [MeSH Supplementary Concept]
- LOC133728 protein, human [MeSH Supplementary Concept]
- Ly-49W receptor [MeSH Supplementary Concept]
- Ly-49W1 receptor [MeSH Supplementary Concept]
- Ly-49W2 receptor [MeSH Supplementary Concept]
- NCR1 protein, human [MeSH Supplementary Concept]
- NCR3 protein, human [MeSH Supplementary Concept]
- NK cell receptor KIR103AS [MeSH Supplementary Concept]
- NK lytic-associated molecule [MeSH Supplementary Concept]
- NKR-P2 protein, rat [MeSH Supplementary Concept]
- NKTR protein, human [MeSH Supplementary Concept]
- Ncr1 protein, mouse [MeSH Supplementary Concept]
- Ncr1 protein, rat [MeSH Supplementary Concept]
- TYROBP protein, human [MeSH Supplementary Concept]
- hcst protein, mouse [MeSH Supplementary Concept]
- nktr protein, mouse [MeSH Supplementary Concept]
- nonspecific cytotoxic cell receptor protein 1 [MeSH Supplementary Concept]
- p50 natural killer cell receptor [MeSH Supplementary Concept]
- p62 natural killer cell receptor [MeSH Supplementary Concept]
- p70 natural killer cell receptor [MeSH Supplementary Concept]
Record concept(s)
- killer cells, natural [MeSH concept]
See also
- cytotoxicity, immunologic [MeSH Descriptor]
- receptors, natural killer cell [MeSH Descriptor]
Semantic type(s)
- Cell [UMLS semantic type]
UMLS correspondences (same concept)
- Natural Killer Cell [NCIt concept]
- Natural killer cell [FMA entity]
- Natural killer cell (cell) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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